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IDA

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Evolutionary Multi-Criterion Optimization

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Adriaan P. Ijzerman

Adriaan P. Ijzerman,Leiden University,Pharmacology,Medicinal Chemistry,Biochemistry

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Adriaan P. Ijzerman

Leiden University

Publications: 155 | Citations: 940

Fields: Pharmacology, Medicinal Chemistry, Biochemistry

Collaborated with 325 co-authors from 1990 to 2011 | Cited by 2639 authors

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Publications (155)

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Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation (Citations: 11)

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Journal: Trends in Pharmacological Sciences - TRENDS PHARMACOL SCI , vol. 32, no. 1, pp. 35-42, 2011

Functionally biased modulation of A 3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers (Citations: 1)

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Journal: Biochemical Pharmacology - BIOCHEM PHARMACOL , vol. 82, no. 6, pp. 658-668, 2011

Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development

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Journal: PLOS One , vol. 6, no. 11, 2011

Allosteric Modulation of Purine and Pyrimidine Receptors

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Published in 2011.

The Structure of the Adenosine Receptors

Published in 2011.

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Citations (940 times by 753 publications)

G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody

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Journal: Nature , vol. 482, no. 7384, pp. 237-240, 2012

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

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Journal: Nature , vol. 482, no. 7386, pp. 547-551, 2012

Global Analysis of Small Molecule Binding to Related Protein Targets

Journal: PLOS Computational Biology - PLOS COMPUT BIOL , vol. 8, no. 1, 2012

L1pred: A Sequence-Based Prediction Tool for Catalytic Residues in Enzymes with the L1-logreg Classifier

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Journal: PLOS One , vol. 7, no. 4, 2012

Docking studies of novel pyrazinopyridoindoles class of antihistamines with the homology modelled H1-receptor

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Journal: Sar and Qsar in Environmental Research - SAR QSAR ENVIRON RES , vol. ahead-of-p, no. ahead-of-p, pp. 1-15, 2012

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Adriaan P. Ijzerman,Leiden University,Pharmacology,Medicinal Chemistry,Biochemistry

Publications (155) BibTeX | RIS | RefWorks Download

Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation (Citations: 11)

Functionally biased modulation of A 3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers (Citations: 1)

Publications (155)

BibTeX | RIS | RefWorks Download