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Dopamine Transporter

,Dopamine Transporter,dopamine transporters,Dopamine Transport,dopamine transporte,dopamine transports,Dopamin Transporter

Dopamine Transporter
Publications: 3,623| Citation Count: 65,402
Stemming Variations: dopamine transporters, Dopamine Transport, dopamine transporte, dopamine transports, Dopamin Transporter
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    • The dopamine transporter (DAT) is a protein regulating dopamine concentration in the synaptic cleft through the re-uptake mechanism. The DAT is the main target of psychostimulants and seems to play a pivotal role in neuronal degeneration and different neuropsychiatric disorders involving the dopamine system...

    Donatella Marazziti, et al. Binding of 3 H-WIN-35,428 and 125 I-RTI-121 to Human Platelet Membrane...

    • The dopamine transporter (DAT1) is a membrane spanning protein that binds the neurotransmitter dopamine and performs re-uptake of dopamine from the synapse into a neuron. The gene encoding DAT1 consists of 15 exons spanning 60 kb on chromosome 5p15.32. Several studies have investigated the possible associations between variants in DAT1 gene and psychiatric disorders. The present study aimed to determine the distribution of the variable number of tandem repeat (VNTR) polymorphism in the 3′ untranslated region of DAT1 in 12 Indian populations...

    L. V. K. S. Bhaskar, et al. Dopamine transporter (DAT1) VNTR polymorphism in 12 Indian populations

    • Dopamine transporter (DAT) is a membrane protein that it is a marker for dopaminergic neurons...

    Alejandro Reynoso Palomar, et al. Expression and Distribution of Dopamine Transporter in Cardiac Tissues...

    • The dopamine transporter (DAT) is a neuronal phosphoprotein and target for psychoactive drugs that plays a critical role in terminating dopaminergic transmission by reuptake of dopamine from the synaptic space...

    J. D. Foster, et al. Regulation of the Dopamine Transporter by Phosphorylation

    • The dopamine transporter (DAT) is a critical recognition site for cocaine and contributes to its significant abuse liability. Accordingly, the development of compounds that target the DAT represents a logical approach in the pharmacological treatment of cocaine abuse. The present study characterized the effects of DAT inhibitors as pretreatments in rhesus monkeys trained to self-administer cocaine under a second-order schedule of i.v. drug delivery. The drugs also were substituted for cocaine to characterize their effectiveness in maintaining drug selfadministration...

    Kimberly P. Lindsey, et al. Effects of Dopamine Transporter Inhibitors on Cocaine Self-Administrat...

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