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Angiotensin Converting Enzyme

ACE,Angiotensin Converting Enzyme,angiotensin converting enzymes,Angiotensin Converting Enzym

Angiotensin Converting Enzyme - ACE
Publications: 8,076| Citation Count: 99,163
Stemming Variations: angiotensin converting enzymes, Angiotensin Converting Enzym
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    • The angiotensin converting enzyme (ACE) is a strong candidate gene for myocardial infarction (MI ). In sertio nd eletio n d im o rphi sm in in tron 16 o f this gene has been inconclusively found to be associated with it. Several new polymorphisms in the ACE gene have been identified and among these, a dimorphism in exon 17, ACE G2350A, has a significant effect on plasma ACE concentrations...

    Saeed M, et al. Association study of the angiotensin-converting enzyme (ACE) gene G235...

    • Angiotensin-converting enzyme (ACE) is a zincand chloride-dependent metallopeptidase that plays a vital role in the metabolism of biologically active peptides. Until recently, much of the inhibitor design and mechanism of action of this ubiquitous enzyme was based on the structures of carboxypeptidase A and thermolysin...

    E. D. Sturrock, et al. What’s new in the renin-angiotensin system?

    • Angiotensin converting enzyme (ACE) inhibition is a well-established principle in the treatment of hypertension, and numerous large scale clinical studies have clearly demonstrated the beneficial effects of inhibiting the renin-angiotensin-aldosterone system (RAS) in hypertension. The clinical success of ACE inhibitors encouraged attempts to inhibit other key enzymes in the regulation of vascular tone, such as the neutral endopeptidase (NEP)...

    Thomas Quaschning, et al. Vasopeptidase inhibition: Effective blood pressure control for vascula...

    • Angiotensin converting enzyme (ACE) inhibition is a common therapeutic modality in the treatment of autosomal recessive polycystic kidney disease (ARPKD). This study was designed to investigate whether chronic inhibition of ACE would have a therapeutic effect in attenuating the progression of renal cystogenesis in an orthologous rat model of ARPKD, the polycystic kidney (PCK) rat...

    Guangfu Jia, et al. Chronic treatment with lisinopril decreases proliferative and apoptoti...

    • The angiotensin-converting enzyme (ACE) is a rate-limiting enzyme in the renin angiotensin system, the enzyme is involved in the vascular remodelling and atherosclerosis...

    Borut Peterlin, et al. DD Genotype of the angiotensin - converting enzyme gene and stroke in ...

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