,Glutathione,glutathioneS,glutathion,glutathionation,glutathionated,glutathionic,glutathionate,Glutathions,glutathionered

Glutathione
Publications: 41,498| Citation Count: 522,217
Stemming Variations: glutathioneS, glutathion, glutathionation, glutathionated, glutathionic
Cumulative Annual
    • Glutathione (GSH) S-transferase is a major detoxification enzyme system that catalyzes the binding of a variety of electrophiles, including reactive forms of chemical carcinogens, to GSH. Green coffee beans fed in the diet induce increased GSH S-transferase activity in the mucosa of the small intestine and in the liver of mice. A potent compound that induces increased GSH S-transferase activity was isolated from green coffee beans and identified as kahweol palmitate...

    Luke K. T. Lamet al. Isolation and Identification of Kahweol Palmitate and Cafestol Palmita...

    • Glutathione (GSH) availability is an important factor in the maintenance of health. Accordingly, blood GSH has been proposed as an indicator of health status...

    JOHN P. RIcHIEet al. Long-term stability of blood glutathione and cysteine in humans

    • Glutathione (GSH) is an abundant intracellular tripeptide that has been implicated as an important regulator of T cell proliferation. The effect of pharmacological regulators of GSH and other thiols on murine T cell signaling, proliferation, and intracellular thiol levels was examined. L-Buthionine-S,R-sulfoximine (BSO), an inhibitor of GSH synthesis, markedly reduced GSH levels and blocked T cell proliferation without significant effect on cell viability. N-acetylcysteine markedly enhanced T cell proliferation without affecting GSH levels...

    Tanja Hadzicet al. The Role of Low Molecular Weight Thiols in T Lymphocyte Proliferation ...

    • Glutathione (GSH) is an important endogenous antioxidant found in millimolar concentrations in the brain. GSH levels have been shown to decrease with aging. Alzheimer's disease (AD) is a neurodegenerative disorder associated with aging and oxidative stress. A(142) has been shown to induce oxidative stress and has been proposed to play a central role in the oxidative damage detected in AD brain. It has been shown that administration of -glutamylcysteine ethyl ester (GCEE) increases cellular levels of GSH, circumventing the regulation of GSH biosynthesis by providing the limiting substrate...

    Debra Boyd-Kimballet al. glutamylcysteine ethyl ester-induced up-regulation of glutathione prot...

    • Glutathione (GSH) is an antioxidant and a biological marker of oxidative stress in the cells. The aims of this study were to measure GSH levels in healthy subjects (n=20) compared to those with chronic renal failure (CRF) (n=10), and investigate the effect of preservatives compared to an oxidizing agent in both normal and CRF human erythrocytes. The red blood cells (RBCs) were incubated with the reagents for various times and then GSH levels were measured...

    Suchada Thongsuwanet al. EFFECT OF PRESERVATIVES ON GLUTATHIONE LEVELS IN HUMAN RED BLOOD CELLS...

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