HT,Hormone Therapy,hormones therapy,hormone therapies,hormonal therapy,hormonal therapies,HORMON THERAPIE

Hormone Therapy - HT
Publications: 6,182| Citation Count: 58,035
Stemming Variations: hormones therapy, hormone therapies, hormonal therapy, hormonal therapies, HORMON THERAPIE
Cumulative Annual
    • Hormonal therapy is an important treatment for advanced/metastatic prostate cancer. But it can induce neuroendocrine (NE) differentiation in prostate cancer cells. These NE cells will secrete manifold neural peptide or hormones which can lead to androgen-independent growth of non-NE tumor cells. When this happens, hormonal therapy becomes useless and indicates bad prognosis...

    Jingwen Wanget al. Neuroendocrine differentiation in prostate cancer

    • Hormonal therapy is a rapidly progressing molecular-targeted therapy for breast cancer, using drugs such as LH-RH agonists, SERMs and aromatase inhibitors. Basic research for estrogen signaling and hormone sensitivity in breast cancer cells strongly contributes to the progression of clinical treatment of breast cancer. However, further problems remain unresolved, for example the accurate prediction of individual response to each hormonal therapy. Moreover, novel combinations with other molecular-targeted therapies might be advance the effectiveness of hormonal therapies...

    Shin-ichi Hayashiet al. Basic research for hormone-sensitivity of breast cancer

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