ITC,Isothermal Titration Calorimetry,Isothermic titration calorimetry,Isothermal titrational calorimetry

Isothermal titration calorimetry (ITC) is a fast and robust method to study the physical basis of molecular interactions. A single well-designed experiment can provide complete thermodynamic characterization of a binding reaction, including Ka, DG, DH, DS and reaction stoichiometry (n). Repeating the experiment at different temperatures allows determination of the heat capacity change (DCP) of the interaction...

Nilshad N. Salim, et al. Isothermal titration calorimetry of RNA