Academic
Keywords
Leukemia Inhibitory Factor

LIF,Leukemia Inhibitory Factor

Leukemia Inhibitory Factor - LIF
Publications: 1,664| Citation Count: 32,672
Cumulative Annual
    • Leukemia inhibitory factor (LIF) is a pleiotropic cytokine known to control the proliferation and survival of stem cells including primordial germ cells and gonocytes...

    CLAIRE PIQUET-PELLORCEet al. Leukemia Inhibitory Factor Expression and Regulation within the Testis

    • Leukemia inhibitory factor (LIF) is a pluripotent cytokine which has a diverse array of effects on hematopoietic and epithelial cells. Depending on the nature of the target cells, these effects can be growth-stimulatory or growth-inhibitory. Receptors for leukemia inhibitory factor (LIFR) have been identified on a variety of hematopoietic and epithelial cells...

    Kapil Dhingraet al. Expression of leukemia inhibitory factor and its receptor in breast ca...

    • Leukemia inhibitory factor (LIF) is a pleiotropic, neuropoietic cytokine found in bovine, murine, and human fetal and adult pituitary cells, mostly in corticotrophs and somatotrophs. In addition, it has been found in a few GHand ACTH-producing human pituitary adenomas. The aim of our study was to investigate the presence of LIF in various morphologic types of human pituitary adenomas. Ninety-eight operated pituitary adenomas diagnosed by light microscopy and classified by pituitary hormone immunocytochemistry and electron microscopy were studied...

    George Kontogeorgoset al. Expression of Leukemia Inhibitory Factor in Human Pituitary Adenomas: ...

    • Leukemia inhibitory factor (LIF) is a cytokine that exerts pleiotropic activities. LIF is a member of the interleukin-6 family of cytokines which share a similar receptor complex and signal through the gp 130 receptor subunit. Several neoplastic cells originating from various tissues express either LIF, its receptor, or both and respond to this cytokine...

    Farhad Ravandiet al. The Role of Leukemia Inhibitory Factor in Cancer and Cancer Metastasis

    • Leukemia inhibitory factor (LIF) is a pleiotropic inflammatory cytokine. A potential role for LIF in the pathogenesis of human breast cancer was recently indicated by the finding that LIF is produced by MDA-MB 231 breast cancer cells and that it stimulates proliferation of the T47D and MCF-7 breast cancer cell lines...

    Ana-Maria Bambergeret al. Differential regulation of the human 'leukemia inhibitory factor' (LIF...

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