Academic
Keywords
Pancreatic Cancer

PC,Pancreatic Cancer,pancreatic cancers,pancreatic cancerous

Pancreatic Cancer - PC
Publications: 12,479| Citation Count: 120,484
Stemming Variations: pancreatic cancers, pancreatic cancerous
Cumulative Annual
    • Pancreatic cancer is a malignancy with an extremely poor prognosis and its incidence has increased in many countries (1‐3). Less than 5% of patients with pancreatic adenocarcinomas survive for more than 5 years. The poor response of advanced pancreatic cancer is attributable to the infiltrative property of pancreatic cancer cells (4), to poor therapeutic options, and to the current incomplete knowledge concerning the pathogenesis and biology of the tumor (3)...

    Hirozumi Sawaiet al. Combined Gemcitabine and α-Interferon Therapy for Pancreatic Cancer: R...

    • Pancreatic cancer is a difficult and unsolved surgical problem. It remains one of the top five causes of cancer-related deaths and has the lowest 5-year survival of any cancer, largely due to late diagnosis, low resection rates, and local recurrence. Clinical trials examining the optimal timing and delivery of adjuvant therapies for pancreatic cancer have yielded controversial results...

    Erika A. Newmanet al. Adjuvant Treatment Strategies for Pancreatic Cancer

    • Pancreatic cancer (PC) is an aggressive malignancy with poor survival. The discovery of microRNAs (miRNAs) has provided a new opportunity to study the disease. Thus far, altered expression of miRNAs has been reported in a wide range of malignancies, including PC, and some miRNAs are associated with PC cell proliferation, invasion, chemoresistance, and patient survival. This review summarizes recent advances with respect to the roles and mechanisms of miRNAs in PC and discusses potential clinical applications...

    Lidong Zhanget al. Roles and Mechanisms of MicroRNAs in Pancreatic Cancer

    • Pancreatic cancer is a disease with a dismal outcome and a 5-year survival rate of under 5%. Recent studies have shown that pancreatic cancer consists of an accumulation of genetic and epigenetic alterations during tumor development as in other human cancers...

    Tamotsu Kurokiet al. Role of Hypermethylation on Carcinogenesis in the Pancreas

    • Pancreatic cancer (PanC) is an extremely life-threatening neoplasm due to its late discovery, rapid progression and resistance to chemoand radiotherapy. In the past years a significant research attention turned to this cancer. Extensive genomic analysis of PanC revealed numerous alterations, however, none of them emerged yet as a key regulator of tumor progression. Our increasing knowledge on the molecular targets in various cancer types started to change their management...

    László Kopperet al. Genomics of pancreatic cancer: Does it make any improvement in diagnos...

Sort by: