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Platelet Activating Factor

PAF,Platelet Activating Factor,platelet activation factor,platelet activating factors,platelet activated factor,platelets activating factors

Platelet Activating Factor - PAF
Publications: 5,628| Citation Count: 55,373
Stemming Variations: platelet activation factor, platelet activating factors, platelet activated factor, platelets activating factors
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    • Platelet-activating factor (PAF; 1-O-Alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a ubiquitous phospholipid that is implicated in the mediation of a wide variety of reproductive processes. To better understand the role of PAF in bovine reproduction, it was designed experiments to: (a) determine whether bull spermatozoa express receptors for PAF and (b) study the effect of exogenous PAF on in vitro sperm physiology (i.e., capacitation, acrosome reaction, motility, and fertilizing ability)...

    Pablo Bosch, et al. BULL SPERMATOZOA EXPRESS RECEPTORS FOR PLATELET-ACTIVATING FACTOR Los ...

    • Platelet activating factor (PAF-acether) is a potent pro-inflammatory mediator. The possible involvement of this molecule in the pathogenesis of chronic erosive arthritis has been investigated using an animal model, antigen-induced arthritis in the rabbit, which closely resembles rheumatoid arthritis. The arthritic joint fluids from rabbits with antigen-induced arthritis contained low levels of PAF-acether in the acute stages of the disease...

    E. R. Pettipher, et al. PAF-acether in chronic arthritis

    • Platelet-Activating Factor (PAF) is a potent lipid mediator involved in physiological and pathological events in the nervous tissue where it can be synthesized by two distinct pathways...

    E. Francescangeli, et al. Activities of Enzymes Involved in the Metabolism of Platelet-Activatin...

    • Platelet-activating factor (PAF) is a potent mediator known to cause bronchoconstriction and increase airways responsiveness.In vitro studies have shown that the effects of PAF on cell function can be very temperature-dependent. The aim of the current study was to investigate the effect of elevated body temperature on numbers of circulating cells and pulmonary function in anesthetized rabbits in response to PAF. PAF was given intravenously, at a dose of 1.2 μg/kg/hour, whereas the control experiments were performed after the animals received a saline infusion...

    M. M. Nieminen, et al. Body temperature modulates the effect of platelet-activating factor (P...

    • Platelet-activating factor (PAF) is a pro-inflammatory lipid mediator that increases vascular permeability by simultaneous activation of two pathways, one dependent on the cyclooxygenase metabolite prostaglandin E2 and the other on the sphingomyelinase metabolite ceramide...

    R. Goggel, et al. The inositol trisphosphate pathway mediates platelet-activating-factor...

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