Academic
Keywords
Reduced Glutathione

,Reduced Glutathione,reducing glutathione,reduce glutathione,reduced glutathion

Reduced Glutathione
Publications: 5,477| Citation Count: 60,135
Stemming Variations: reducing glutathione, reduce glutathione, reduced glutathion
Cumulative Annual
    • Reduced glutathione (GSH) is an intracellular molecule essential for many aspects of cell physiology and defense. Determination of GSH has been used to identify potential anti-cancer drugs and for the assessment of drug toxicity via generation of oxidative stress. The described protocol was designed to modify existing protocols for the fluorescent detection of intracellular GSH in a high throughput 96-well microplate format. Dibromobimane was used to label intracellular GSH, and an additional dye, Hoechst 33342 was used to measure cell density for data normalization...

    David P. Coet al. High Throughput Method for Assessment of Cellular Reduced Glutathione ...

    • Reduced glutathione (GSH) is a tripeptide that is involved in critical cellular functions, including detoxification of reactive metabolic intermediates and foreign chemicals, and maintenance of the thiol redox status...

    James F. Rebbeoret al. ATP-DEPENDENT GSH AND GLUTATHIONE S-CONJUGATE TRANSPORT IN SKATE LIVER...

    • Reduced glutathione (GSH) is the most prevalent non-protein thiol in animal cells. Its de novo and salvage synthesis serves to maintain a reduced cellular environment and the tripeptide is a co-factor for many cytoplasmic enzymes and may also act as an important posttranslational modification in a number of cellular proteins. The cysteine thiol acts as a nucleophile in reactions with both exogenous and endogenous electrophilic species...

    Danyelle M. Townsendet al. Dossier : Oxidative stress pathologies and antioxidants The importance...

    • Reduced glutathione (GSH) is a key component of the cellular defense cascade against injury caused by reactive oxygen species...

    MAURA FLOREANIet al. Melatonin maintains glutathione homeostasis in kainic acid-exposed rat...

    • Reduced glutathione (GSH) is the most abundant source of nonprotein thiols in plant cells. It has multiple functions in plants, including cell differentiation, cell death and senescence, pathogen resistance, enzymatic regulation, as an antioxidant, in formation of phytochelatins, detoxification of xenobiotics, and also acts as a storage and transport form of reduced sulfur. Along with its oxidized form (GSSG), it acts as a redox couple important for maintaining cellular homeostasis, playing a key role in diverse signaling systems in plants...

    S. Srivalliet al. Role of Glutathione in Abiotic Stress Tolerance

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