,Bone Disease,bone diseases

Bone Disease
Publications: 3,718| Citation Count: 37,252
Stemming Variations: bone diseases
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    • Bone disease is a hallmark of multiple myeloma (MM). Occurring in the majority of MM patients, it is associated with bone pain, fractures, and hypercalcemia and has major impacts on quality of life. Furthermore, bone resorptionactivityhasbeenshowntobeanindependent risk factor for overall survival in patients with symptomatic MM...

    ORHAN SEZER. Myeloma Bone Disease: Recent Advances in Biology, Diagnosis, and Treat...

    • Bone disease is a hallmark of multiple myeloma (MM) and contributes to most of the debilitating morbidity associated with this disease. Bone lesions result not only from the direct deposits of MM cells within the bone, but also from the release of soluble factors by both the tumor and the microenvironment, resulting in the stimulation of osteoclast activity and bone resorption...

    Noopur Rajeet al. Introduction: the evolving role of bisphosphonate therapy in multiple ...

    • Bone disease is a common disorder of bone remodeling and mineral metabolism, which affects patients with chronic kidney disease. Minor changes in the serum level of a given mineral can trigger compensatory mechanisms, making it difficult to evaluate the role of mineral disturbances in isolation. The objective of this study was to determine the isolated effects that phosphate and parathyroid hormone (PTH) have on bone tissue in rats. Male Wistar rats were subjected to parathyroidectomy and 5/6 nephrectomy or were sham-operated...

    Daniella G. Batistaet al. The Bone Histology Spectrum in Experimental Renal Failure: Adverse Eff...

    • Bone disease is a common feature of multiple myeloma (MM). The goal of this study was to assess the prognostic significance of urinary markers of bone metabolism in MM...

    Khalil Kargar Samaniet al. Prognostic value of urinary pyridinium crosslinks and their derivative...

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