Academic
Keywords
Staphylococcus Aureus

SA,Staphylococcus Aureus,Staphylococcus aureu,Staphylococcu aureus

Staphylococcus Aureus - SA
Publications: 26,484| Citation Count: 255,357
Stemming Variations: Staphylococcus aureu, Staphylococcu aureus
Cumulative Annual
    • Staphylococcus aureus is a common human pathogen, and over the past 90 years has been increasingly recognized as an important cause of pneumonia. The epidemiology of staphylococcal pneumonia has changed over this time period, and S. aureus is now a frequent cause of both community-acquired and hospital-acquired pneumonia including ventilator-associated pneumonia. This article reviews the important changes in the epidemiology and microbiology of S. aureus, the clinical features of S. aureus pneumonia, and considerations in antibiotic therapy for this disease...

    Sarah D. Haessleret al. Pneumonia Caused by Staphylococcus aureus

    • Staphylococcus aureus is an opportunistic pathogen and one of the major causes of nosocomial and community-acquired infections. Adaptation to changing conditions and a wide spectrum of diseases ranging from superficial to serious life-threatening infections and toxicoses is conferred by a formidable arsenal of pathogenicity and virulence factors. Besides their remarkable ability to acquire multiple resistance determinants, staphylococci adopt additional strategies to evade antibiotic challenge and host defenses...

    Maria M. Sennet al. B Activity in a Staphylococcus aureus hemB Mutant

    • Staphylococcus aureus is an important human pathogen and represents a growing public health burden owing to the emergence and spread of antibiotic-resistant clones, particularly within the hospital environment. Despite this, basic questions about the evolution and population biology of the species, particularly with regard to the extent and impact of homologous recombination, remain unanswered...

    Edward J. Feilet al. How Clonal Is Staphylococcus aureus?

    • Staphylococcus aureus is a versatile and dangerous pathogen and one of the major causes of communityacquired and hospital-acquired infections. The rise of multidrug-resistant strains of S. aureus requires the development of new antibiotics with previously unexploited mechanisms of action, such as inhibition of the -ketoacyl-acyl carrier protein (ACP) synthase III (FabH). This enzyme initiates fatty acid biosynthesis in a bacterial type II fatty acid synthase, catalyzing a decarboxylative condensation between malonyl-ACP and an acyl coenzyme A (CoA) substrate and is essential for viability...

    Xin Heet al. Purification, Characterization, and Identification of Novel Inhibitors...

    • Staphylococcus aureus is a pathogen often found in pneumonia and sepsis. In the context of the resistance of this organism to conventional antibiotics, an understanding of the regulation of natural endogenous antimicrobial molecules is of paramount importance. Previous studies have shown that both human and mouse airways express a variety of these molecules, including defensins, cathelicidins, and the four-disulfide core protein secretory leukocyte protease inhibitor...

    J. W. McMichaelet al. Antimicrobial Activity of Murine Lung Cells against Staphylococcus aur...

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