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toxoplasma gondii

,toxoplasma gondii

toxoplasma gondii
Publications: 5,606| Citation Count: 61,670
Cumulative Annual
    • Toxoplasma gondii is a protozoan parasite that infects a wide variety of warm-blooded animals and humans, in which it causes opportunistic disease. As an obligate intracellular parasite, T. gondii must invade a host cell to survive and replicate during infection. Recent studies suggest that T. gondii secretes a variety of proteins that appear to function during invasion or intracellular replication. These proteins originate from three distinct regulated secretory organelles called micronemes, rhoptries and dense granules...

    Vern B. CarruthersU. Armed and dangerous: Toxoplasma gondii uses an arsenal of secretory pr...

    • Toxoplasma gondii is an opportunistic protozoan parasite that differentiates into latent cysts (bradyzoite) that can be reactivated during immunosuppression. TgSRCAP ( Toxoplasma gondii Snf2-related CBP activator protein) is a SWI2/SNF2 family chromatin remodeler whose expression increases during cyst development...

    Karuna C. Nallaniet al. Identification of proteins interacting with Toxoplasma SRCAP by yeast ...

    • Toxoplasma gondii is an important cause of clinical disease in fetuses, infants and immunocompromised patients. Since the discovery of T. gondii 100 years ago, this pathogen and the host's immune response to toxoplasmosis have been studied intensely. This has led to the development of a working model of immunity to T. gondii, and has also resulted in fundamental new insights into the role of various cytokines in resistance to infection...

    Elia D Taitet al. Advances in understanding immunity to Toxoplasma gondii

    • Toxoplasma gondii is a well-described ubiquitous Apicomplexan protozoan parasite that is an important opportunistic pathogen. The factors affecting the transition of tachyzoites to the latent bradyzoite stage remain to be defined. The induction of bradyzoite development in vitro has been linked to temperature, pH, mitochondrial inhibitors, sodium arsenite, and many of the other stressors associated with heat shock protein (hsp) induction...

    LOUIS M. WEISSet al. Bradyzoite Development in Toxoplasma gondii and the hsp70 Stress Respo...

    • Toxoplasma gondii is a protozoan parasite that typically manifests as multiple b rain lesions of varying sizes. Toxoplasmosis usually causes neurological complications in immunocompromised patients while it is mostly asymptomatic in healthy subjects. A 19-year-old Peruvian woman presented with seizure, and MRI of the brain disclosed a nodular lesion in the left parietal lobe. This case of toxoplasmosis in an immunocompetent patient required extensive differential diagnoses and treatments...

    Young Il Kimet al. Toxoplasmosis Showing Atypical Brain Lesion in an Immunocompetent Pati...

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