Academic
Keywords
Transcription Regulation

,Transcription Regulation,transcriptional regulation,Transcriptional Regulators,transcriptional regulator,transcriptional regulations,transcription re

Transcription Regulation
Publications: 17,928| Citation Count: 310,204
Stemming Variations: transcriptional regulation, Transcriptional Regulators, transcriptional regulator, transcriptional regulations, transcription regulators
Cumulative Annual
    • Transcriptional regulation is a pivotal process that confers cellular identity and modulates the biological activities within a cell. In embryonic stem cells (ESCs), the intricate interplay between transcription factors and their targets on the genomic template serves as building blocks for the transcriptional network that governs self-renewal and pluripotency. At the heart of this complex network is the transcription factor trio, Oct4, Sox2 and Nanog, which constitute the ESC transcriptional core...

    Jian-Chien Dominic Henget al. Transcriptional Regulation in Embryonic Stem Cells

    • Transcriptional regulation is an inherently noisy process. The origins of this stochastic behavior can be traced to the random transitions among the discrete chemical states of operators that control the transcription rate and to finite number fluctuations in the biochemical reactions for the synthesis and degradation of transcripts...

    Thomas B. Kepleret al. Stochasticity in Transcriptional Regulation: Origins, Consequences, an...

    • Transcriptional regulation is a complex multistep process involving numerous protein-protein and protein nucleic acid interactions influenced by post-translational modifications. Both sequence specific DNA binding factors as well as coregulator proteins are targets of sumoylation, and many of the paradigms for SUMO-mediated effects have been identified in the context of transcriptional regulation...

    Jorge A. Iñiguez-Lluhí. SUMO Modification and Transcriptional Regulation

    • Transcriptional regulation is a key mechanism that allows cells to make the appropriate amount of proteins at the right time. This is mediated by transcription factors that respond to specific signals and regulate expression of the relevant genes...

    M. Madan Babu. Evolutionary and Temporal Dynamics of Transcriptional Regulatory Netwo...

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