Academic
Keywords
Bronchial Asthma

BA,Bronchial Asthma,Bronchiale asthma

Bronchial Asthma - BA
Publications: 4,084| Citation Count: 27,959
Stemming Variations: Bronchiale asthma
Cumulative Annual
    • Bronchial asthma (BA) is a common chronic inflammatory disease characterized by hyperresponsive airways, excess mucus production, eosinophil activation, and the production of IgE. The complement system plays an immunoregulatory role at the interface of innate and acquired immunities...

    Koichi Hasegawaet al. Variations in the C3, C3a receptor, and C5 genes affect susceptibility...

    • Bronchial asthma (BA) is a multifactorial disorder, the development of which is affected by both environmental and genetic factors. The complement system plays an important role in immunological response against invading microorganisms. It has been shown that complement-C3-deficient mice have reduced inflammation of asthmatic airways...

    Hiroki Inoueet al. Association study of the C3 gene with adult and childhood asthma

    • Bronchial asthma is a multifactorial disease whereby both environmental and genetic factors contribute to its aetiology and/or clinical severity. The aim of this study was to examine the association of 22 cytokine gene polymorphism in the Macedonian population with bronchial asthma (BA). The sample of the population comprised of 301 normal unrelated individuals and 74 patients with BA...

    Dejan Trajkovet al. Association of cytokine gene polymorphisms with bronchial asthma in ma...

    • Bronchial asthma is a complicated and diverse disorder affected by genetic and environmental factors, with Th2-type inflammation dominant in its pathogenesis. However, the underlying molecular mechanism of bronchial asthma is still poorly understood. Microarray technology, now one of the most powerful tools for functional genomics, has been used in several trials to dissect the pathogenesis of bronchial asthma, providing some novel pathogenic mechanisms as well as information about gene-expression profiling...

    Kenji Izuharaet al. Gene expression patterns in asthma

    • Bronchial asthma is a common disease and an important cause of morbidity among both children and adults. Tobacco smoking, both active and passive i.e., exposure to environmental tobacco smoke (ETS) has got important effects on asthma. Smoking by adults causes bronchial irritation and precipitates acute episodes. It also increases bronchial responsiveness and causes airway sensitization to several occupational allergens. Smoking may also increase the disease severity...

    S. K. Jindalet al. The relationship between tobacco smoke & bronchial asthma

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