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Keywords
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Keywords
fibroblast growth factor 2
FGF2,fibroblast growth factor 2,Fibroblast Growth Factors 2,Fibroblastic Growth Factor 2
fibroblast growth factor 2 - FGF2
Publications: 1,611
|
Citation Count: 26,083
Stemming Variations:
Fibroblast Growth Factors 2, Fibroblastic Growth Factor 2
Cumulative
Annual
Definition Context
(5)
Fibroblast growth factor-2 (FGF-2) is a potent regulator of many cellular functions and phenomena, including cell proliferation, differentiation, survival, adhesion, migration, motility and apoptosis, and processes such as limb formation, wound healing, tumorigenesis, angiogenesis, vasculogenesis and blood vessel remodeling...
Karen A. Detillieux
,
et al.
Review B iological activities of fibroblast growth factor-2 in the adu...
Fibroblast growth factor-2 (FGF2) is a pleiotropic heparin-binding growth factor endowed with a potent angiogenic activity in vitro and in vivo...
Raffaella Giavazzi
,
et al.
Modulation of Tumor Angiogenesis by Conditional Expression of Fibrobla...
Fibroblast Growth Factor-2 (FGF2) is a major inducer of neovascularization (angiogenesis). Heparin activates FGF2 by favoring formation of ternary complexes with its cellular receptors (FGFRs). Controlled 2-O-desulfation followed by exhaustive periodate oxidation/borohydride reduction has been used to generate sulfation gaps within the prevalent heparin sequences, building-up arrays of pentasulfated trisaccharides (PST, consisting of a 2-O-sulfated iduronic acid flanked by two N,6-disulfated glucosamines) spaced by reduced, glycol-split uronic acid (sU) residues...
Benito Casu
,
et al.
Short Heparin Sequences Spaced by Glycol-Split Uronate Residues Are An...
Fibroblast growth factor-2 (FGF-2) is a potent mitogen and angiogenic factor normally absent from the adult circulation...
D. J. Hill
,
et al.
Increased Levels of Serum Fibroblast Growth Factor2 in Diabetic Pregna...
Fibroblast growth factor 2 (FGF-2) is a multifunctional mitogen present in CUGand AUG-initiated forms, referred to as ‘hi’ and ‘lo’ FGF-2, respectively...
Cheryl J. A. Hirst
,
et al.
High levels of CUG-initiated FGF2 expression cause chromatin compactio...
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Publications
(1611)
Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate
Laurence Duchesne
,
Vivien Octeau
,
Rachel N. Bearon
,
Alison Beckett
,
Ian A. Prior
,
Brahim Lounis
,
David G. Fernig
Journal:
PLOS Biology - PLOS BIOL
, vol. 10, no. 7, 2012
Adenovirus-mediated E2-EPF UCP Gene Transfer Prevents Autoamputation in a Mouse Model of Hindlimb Ischemia
Jung Hwa Lim
,
Hyo Jung Shin
,
Kyeong-Su Park
,
Chan Hee Lee
,
Cho-Rok Jung
,
Dong-Soo Im
Journal:
Molecular Therapy - MOL THER
, vol. 20, no. 4, pp. 778-787, 2012
MicroRNA Signatures in Tumor Tissue Related to Angiogenesis in Non-Small Cell Lung Cancer
Tom Donnem
,
Christopher G. Fenton
,
Kenneth Lonvik
,
Thomas Berg
,
Katrine Eklo
,
Sigve Andersen
,
Helge Stenvold
,
Khalid Al-Shibli
,
Samer Al-Saad
,
Roy M. Bremnes
,
Lill-Tove Busund
Journal:
PLOS One
, vol. 7, no. 1, 2012
Fibroblast growth factor and ornithine decarboxylase 5′UTRs enable preferential expression in human prostate cancer cells and in prostate tumors of PTEN−/− transgenic mice
M Moussavi
,
N Moshgabadi
,
L Fazli
,
E Leblanc
,
K Zhang
,
W Jia
,
P S Rennie
Journal:
Cancer Gene Therapy
, vol. 19, no. 1, pp. 19-29, 2012
Therapeutic potential of fibroblast growth factor-2 for hypertrophic scars: upregulation of MMP-1 and HGF expression
Hitomi Eto
,
Hirotaka Suga
,
Noriyuki Aoi
,
Harunosuke Kato
,
Kentaro Doi
,
Shinichiro Kuno
,
Yasuhiko Tabata
,
Kotaro Yoshimura
Journal:
Laboratory Investigation - LAB INVEST
, vol. 92, no. 2, pp. 214-223, 2012