Academic
Keywords
Isolated Systolic Hypertension

ISH,Isolated Systolic Hypertension,isolated systolic hypertensive

Isolated Systolic Hypertension - ISH
Publications: 715| Citation Count: 9,037
Stemming Variations: isolated systolic hypertensive
Cumulative Annual
    • Isolated systolic hypertension (ISH) is an important cause of strokes and heart failure among the elderly, but it is difficult to control in some elderly patients, even with combination antihypertensive therapy. The presence of a prominent reflection wave in the arterial pulse-wave profile of such patients signifies that adjuvant nitrate therapy may prove effective in lowering pulse pressure...

    Gordon S. Stokes. Nitrates as adjunct hypertensive treatment

    • Isolated systolic hypertension (ISH) is the most common type of hypertension and the most difficult type to control with antihypertensive therapy. ISH, by definition, is wide pulse pressure hypertension resulting largely from excessive large artery stiffness and representing an independent risk factor for cardiovascular disease in the older aged population. Two major intervention studies of ISH have shown significant benefit in reducing systolic blood pressure with active drug therapy, including thiazide diuretics and calcium receptor antagonists...

    Stanley S. Franklin. Is there a preferred antihypertensive therapy for isolated systolic hy...

    • Isolated systolic hypertension (ISH) is the dominant form of hypertension in the elderly. It is associated with increased arterial pulse pressure, to which an early-returning and magnified pulse-wave reflection makes an important contribution. Treatment of ISH with diuretics, calcium channel blockers (CCBs), and angiotensin II inhibitors is effective in reducing systolic blood pressure, preventing cardiovascular morbid events, and lowering mortality; these agents may have to be used in combination to achieve the systolic blood pressure goal of < 140 mm Hg...

    Gordon S. Stokes. Treatment of isolated systolic hypertension

    • Isolated systolic hypertension is a common condition in individuals aged older than 60 years. However, isolated systolic hypertension has also been described in young individuals, although the mechanisms are poorly understood...

    Carmel M. McEnieryet al. Increased Stroke Volume and Aortic Stiffness Contribute to Isolated Sy...

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