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Adaptive Response

,Adaptive Response,adaptive responsive,adaptive responses,adapts responses,adaptive responsible,Adaptive Responsiveness,adaptation responses,adapt res

Adaptive Response
Publications: 6,314| Citation Count: 86,027
Stemming Variations: adaptive responsive, adaptive responses, adapts responses, adaptive responsible, Adaptive Responsiveness
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    • Adaptive response (AR) is a well-documented phenomenon by which cells or organisms exposed to low dose of a genotoxicant become less sensitive to subsequent highdose exposure to the same or another genotoxicant. AR, if induced can modify the efficacy leading to drug or radioresistance, during anti-neoplastic drug or radiation treatment. Contradictions exist in AR induction by different genotoxicants with respect to the biomarkers, time schedules, and inter-individual variability, reflecting the complexity of AR in eukaryotic cells...

    A. P. Krishnaja, et al. Variability in cytogenetic adaptive response of cultured human lymphoc...

    • The adaptive-response is an inducible repair system of E. coli which reduces the mutagenic and cytotoxic effects of alkylation damage (Samson and Cairns, 1977). In adapted cells (cells exposed to sublethal doses of alkylating agents) the induction of W-reactivation and W-mutagenesis by alkylating agents is almost totally blocked...

    Martine Defais, et al. Effect of the adaptive response on the induction of the SOS pathway in...

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