Academic
Keywords
Diabetic Nephropathy

DN,Diabetic Nephropathy,diabetes nephropathy,diabetic nephropathies

Diabetic Nephropathy - DN
Publications: 6,180| Citation Count: 77,034
Stemming Variations: diabetes nephropathy, diabetic nephropathies
Cumulative Annual
    • Diabetic nephropathy (DN) is a severe complication of diabetes which may progress to end-stage renal disease (ESRD). Chronic hyperglycemia is considered as the major initiator of DN, either by creation of oxidative stress or by induction of growth factors and cytokines. Moreover, dyslipidemia plays a role in DN progression. The aim of our study was to examine the changes in lipid profile, malondialdehyde (MDA), transforming growth factor-β1 (TGF-β1) and angiotensin II (Ang II) levels in type 2 diabetic patients associated with kidney disease...

    HO El-mesallamyet al. The association of TGF-β1, angiotensin II and oxidative stress with di...

    • Diabetic nephropathy (DN) is a serious complication in a subgroup of patients with insulin dependent diabetes mellitus (IDDM)...

    B. Walderet al. Genetic heterogeneity in the renin-angiotensin system and the risk of ...

    • Diabetic nephropathy (DN) is a common complication of diabetes types 1 and 2. One of the hallmarks of DN is the development of mesangial expansion, which occurs through accumulation of extracellular matrix (ECM) components. Altered local gene expression of humoral factors (eg, transforming growth factor-â, connective tissue growth factor, and platelet-derived growth factor) can lead to increased production of ECM components (eg, fibronectin and collagen IV) or decreased degradation through matrix metal oproteinases (eg, MMP-1, MMP-2)...

    Daniela Hohenadelet al. Gene expression in diabetic nephropathy

    • Diabetic nephropathy is a progressive renal disease with thickening of the gbomerular basement membrane and mesangial expansion and proliferation as histological hallmarks. The presence of the glycosaminoglycan side chains of heparan sulfate proteoglycan, an important constituent of the glomerular basement membrane, is decreased in diabetic nephropathy proportionally to the degree of proteinuria...

    JOHAN W. VAN DER PIJLet al. Danaparoid Sodium Lowers Proteinuria in Diabetic Nephropathy

    • Diabetic nephropathy is a serious and frequent complication of insulin-dependent diabetes mellitus (IDDM) that has a strong genetic component. Several case-control studies have reported conflicting results with regard to the role of angiotensinogen gene polymorphisms, specifically the M235T T allele, in the development of diabetic nephropathy. The primary limitation of the case-control approach is that bias may be introduced by unrecognized differences in the populations selected for cases and control subjects...

    John J. Roguset al. Diabetic Nephropathy Is Associated With AGT Polymorphism T235 Results ...

Sort by: