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STUDIES ON PARAKERATOSIS IN SWINE

STUDIES ON PARAKERATOSIS IN SWINE,J. W. STEVENSON,I. P. EARLE

STUDIES ON PARAKERATOSIS IN SWINE   (Citations: 20)
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rarely resulted in mortality. The condition has appeared most often in pigs from 10 to 16 weeks of age and has been almost completely limited to fall-winter feeding trials. Although pigs with severe symptoms of parakeratosis have had sig- nificantly lower levels of serum vitamin A than normal animals, oral therapy with massive doses of vitamin A acetate has been of no ap- parent benefit to improvement either of disease conditions or of serum vitamin A level. Whether avitaminosis A was due to depressed food consumption or failure to absorb vitamin A from the digestive tract was not determined. Attempts to alter the course of parakeratosis by changes in quality of dietary protein were also ineffective. The association between high calcium content in swine diets and in- tensified symptoms of parakeratosis was reported by Ellis (1953). Results of this experiment, which was designed to investigate a "rickets- t Animal and Poultry Husbandry Research Branch, Agricultural Research Service, Agricultural
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    • ...The relationship between dietary zinc and vitamin A metabolism has recently received attention (for review see References 1 and 2). Several studies (3-7) indicate that zinc is necessary for normal concentration of vitamin A in blood plasma...
    • ...In zinc-deficient (ZD) rats (3-5), swine (6), and lambs (7), low plasma vitamin A levels were observed despite adequate amounts of vitamin A in the diet and in the liver, after zinc supplementation, the plasma vitamin A levels increased to within the normal range (4)...

    Deborah L Balyet al. Studies of marginalzinc deprivation in rhesus monkeys. Ill. Effects on...

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