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St. George's Respiratory Questionnaire: MCID

St. George's Respiratory Questionnaire: MCID,10.1081/COPD-200050513,Copd-journal of Chronic Obstructive Pulmonary Disease,Paul W. Jones,Yvonne Forde

St. George's Respiratory Questionnaire: MCID   (Citations: 28)
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    • ...Primary outcomes were change from baseline in disease-specific quality of life as assessed by the St George’s Respiratory Questionnaire (SGRQ) total score and the total number of exacerbations (moderate plus severe). ...

    C R van Weteringet al. Short and long-term efficacy of a community-based COPD management prog...

    • ...Specific pharmacological therapy for COPD helps to prevent and control symptoms, reduce the frequency and severity of exacerbations, improve health status and improve exercise tolerance [1-3]...
    • ...They reduce air trapping and improve emptying of the lungs, thereby reducing lung volumes, improving symptoms such as breathlessness and increasing exercise capacity [1,5]...
    • ...For patients with Stage II (moderate) or more severe COPD, regular treatment with a twice-daily LABA such as formoterol or salmeterol, or a long-acting muscarinic antagonist (LAMA) such as tiotropium, is more effective and convenient than treatment with the shorter-acting agents [1]...
    • ...No one long-acting bronchodilator is recommended over another in management guidelines [1], because few studies have specifically compared different LABAs [19,20]...
    • ...The choice therefore depends on availability and the response of the individual patient [1]...
    • ...A summary is provided in Table 2 [1,25-31]...
    • ...In some [29,30,48,71], but not all [23,28,31,33,36] studies, improvements compared with placebo exceeded the MCID of 4 units for the SGRQ [72]...
    • ...Asthma is likely to present early in life (often in childhood) and be associated with symptoms which vary from day to day, often at night or in the early morning; subjects often have a history of asthma in their family and airflow limitation tends to be more reversible than in COPD [1,86]...
    • ...Commonly occurring LABA class effects include palpitations, headache and tremor, which may limit the dose that can be tolerated, especially in some older patients [1]...
    • ...LABAs are associated with known class effects, the most significant being related to cardiac safety [1]...
    • ...Tiotropium, the only once-daily inhaled bronchodilator currently available, is a LAMA that significantly improves lung function, increases exercise capacity and improves effectiveness of pulmonary rehabilitation, improves health status, and reduces exacerbations [1,79]...
    • ...and is associated with anticholinergic side effects, such as dry mouth (most commonly) and urinary retention (rarely) [1]...

    Donald P Tashkinet al. Long-acting beta-agonists in the management of chronic obstructive pul...

    • ...In accordance with the study’s inclusion criteria, subjects had clinically diagnosed COPD as defined by the American Thoracic Society (ATS) [33]...
    • ...Based on the criteria of the American Thoracic Society [33], 42.7% of the subjects were at a severe stage of COPD, 41.7% were at a moderate stage, and 15.5% were at a mild stage...
    • ...A decrease of more than 4 units in the SGRQ score is indicative of positive functional change [43]...

    Aileen W. K. ChanAlbertet al. Effectiveness of a Tai chi Qigong program in promoting health-related ...

    • ...A number of methods are used to define the MCID,...

    S J Singhet al. Minimum clinically important improvement for the incremental shuttle w...

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