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Prevalence of Antibodies to Syphilis among Blood Donors in Accra, Ghana

Prevalence of Antibodies to Syphilis among Blood Donors in Accra, Ghana,Andrew Anthony Adjei,William Kudzi,Henry Armah,Theophilu Adiku,Albert George,B

Prevalence of Antibodies to Syphilis among Blood Donors in Accra, Ghana   (Citations: 8)
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SUMMARY: Several infectious diseases have been found to be associated with transfusion of blood and blood components. Reports from studies conducted in many African countries indicate a high incidence of blood- borne pathogens such as syphilis infections among healthy blood donors. The prevalence of syphilis antibodies in blood donors in Ghana is not known. This study was therefore conducted in order to determine the prevalence of antibodies to syphilis among blood donors seen between the months of January and March 2003 at the National Blood Transfusion Service, Accra area (Blood Bank) at the Korle-Bu Teaching Hospital, Accra, Ghana. The presence of antibodies specific for syphilis was tested using Veneral Disease Research Laboratory and particle agglutination test kit. A sero-prevalence rate of 7.5% was found. Our sample of blood donors was largely comprised of male subjects (500 out of 536 donors, and only 1 out of the 36 screened female donors was positive), making sex comparisons statistically undesirable. In both sexes, the age distribution of subjects positive for syphilis antibodies was from 19 - 54 (median age, 32) years. In conclusion, our results indicate that syphilis is prevalent among healthy blood donors in Ghana, and that there is a need to introduce the screening of donated blood for syphilis in Ghana.
Published in 2003.
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    • ...Similarly, the seroprevalence of syphilis (1.3%) in this study is lower than the 3.6% in Maiduguri [23], 7.5% in Ghana [30], 12.8% in Ethiopia [31] and 12.7% in Tanzania [32] but is higher than the 0.1% Table 5 Socio–demographic characteristics of blood donors by hepatitis B and C virus seropositivity at Gondar University Teaching Hospital in Northwest Ethiopia 2003-2007 Characteristics HBV Positive...

    Belay Tessemaet al. Seroprevalence of HIV, HBV, HCV and syphilis infections among blood do...

    • ...these infections previously reported in the general public in Ghana, mainly healthy blood donors and pregnant women [35-44]...
    • ...This study found higher overall seroprevalence rates of HIV (4.9%), HBV (11.7%), HCV (18.7%) and syphilis (7.9%) in Ghanaian PONEIHD, as compared to the seroprevalence of these infections previously reported in the general public in Ghana, mainly healthy blood donors and pregnant women [35-44]...

    Andrew A Adjeiet al. Correlates of HIV, HBV, HCV and syphilis infections among prison inmat...

    • ...Most of the donor were males 1424 (88.4%), aged between 20–39 years (72.2%) and were mainly replacement 1125 (69.8%) rather than voluntary donors 474 (29.4%), which is consistent with observations in several other studies in Africa [7-9]...

    Pius M Magesaet al. Seroprevalence of human immunodeficiency virus, hepatitis B and C viru...

    • ...The seroprevalence of Treponema pallidum, the causative agent of syphilis, is between 7?5 and 13?5% among blood donors in Ghana (Adjei et al., 2003; Ampofo et al., 2002), and 5?6% among antenatal and gynaecological clinic attendants in Accra, Ghana (Apea-Kubi et al., 2004)...
    • ...However, the seroprevalence of HBsAg and syphilis among the prison inmates and officers was comparable to that previously reported in the general Ghanaian population (Acquaye & Mingle, 1994; Adjei et al., 2003; Ampofo et al., 2002; Apea-Kubi et al., 2004; Damale et al., 2005; Martinson et al., 1996, 1998; Sarkodie et al., 2001)...

    Andrew A. Adjeiet al. Prevalence of human immunodeficiency virus, hepatitis B virus, hepatit...

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