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Seroprevalence of Hepatitis C Virus Antibodies Amongst Blood Donors in Ibadan, Southwestern, Nigeria

Seroprevalence of Hepatitis C Virus Antibodies Amongst Blood Donors in Ibadan, Southwestern, Nigeria,A. O. Udeze,E. Donbraye,W. F. Sule,A. Fadeyi,L. N

Seroprevalence of Hepatitis C Virus Antibodies Amongst Blood Donors in Ibadan, Southwestern, Nigeria  
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This study was carried out to determine the prevalence of antibodies to HCV among blood donors in Ibadan and to generate data which may be useful to appropriate health authorities. The subjects included in this study were 200 (184 males and 16 females; aged 20 to 60 years) blood donors in the blood bank of UCH, Ibadan who consented voluntarily after thorough explanation of the purpose of the study. The samples were tested for the presence of antibodies to HCV using rapid ELISA technique developed by RIGHTCHOIC E Diagnostics, Israel. Analysis of the result showed that 16 (8.0%) of the donors had antibodies to HCV. The result also showed highest HCV antibody prevalence of 11.5% amongst blood donors in the age range 30-39 years. Statistical analysis, however, showed no significant difference (p>0.05) between the prevalence rates of the male and female individuals. There was, however, no statistical association (p > 0.05) between age of the patients and prevalence of HCV antibodies. Our findings further confirm the presence of hepatitis C viru s infection among blood donors in Nigeria. Routine HCV screening of blood donors is therefore recommended in order to reduce the risk of post transfusion hepatitis C.
Published in 2009.
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