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Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma

Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma,10.1245/s10434-008-0295-2,Annals of Surgical Oncology,Matt

Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma   (Citations: 25)
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Introduction  Actual 5-year survival rates of 10–18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term survival and patterns of recurrence in patients treated for PC with contemporary staging and multimodality therapy. Methods  We analyzed 329 consecutive patients with PC evaluated between 1990 and 2002 who underwent resection. Each received a multidisciplinary evaluation and a standard operative approach. Pre- or postoperative chemotherapy and/or chemoradiation were routine. Surgical specimens of 5-year survivors were rereviewed. A multivariate model of factors associated with long-term survival was constructed.
Journal: Annals of Surgical Oncology - ANNALS SURG ONCOLOGY , vol. 16, no. 4, pp. 836-847, 2009
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    • ...The two goals of this study are: (1) to identify and evaluate sources of variability in surgical technique and methods of pathologic review among patients with resectable PC prior to enrollment in multi-institutional clinical trials of postoperative adjuvant therapy, and (2) to examine the completeness of documentation of these variables in the operative and pathology reports generated for these patients...

    Matthew H. G. Katzet al. Standardization of Surgical and Pathologic Variables is Needed in Mult...

    • ...Kidger et al. 2009 18 (1) Unsystematic consideration of patient-related factors (comorbidity, psychosocial situation, patient wishes), privileged...
    • ...Amir et al. 2004 19 (1) Role in ensuring the co-ordination, communication and planning of the team not recognised outside the team...

    Benjamin W. Lambet al. Quality of Care Management Decisions by Multidisciplinary Cancer Teams...

    • ...Katz et al. [11] reported that late recurrence after 5 years occurred in seven patients, most frequently on the lung, the latest at 6.7 years and the latest cancer-related death occurred at 7.6 years...
    • ...Katz et al. [11] also described that of the 17 5-year survivors who died of recurrent disease; death occurred at a median of 15 months (recurrence to last follow-up, range, 0.7–51 months)...

    Kazuaki Shimadaet al. Analysis of 5Year Survivors After a Macroscopic Curative Pancreatectom...

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