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Genome-wide methylation patterns in normal and uniparental early mouse embryos

Genome-wide methylation patterns in normal and uniparental early mouse embryos,10.1093/hmg/10.26.2983,Human Molecular Genetics,Sheila C. Barton,Kathar

Genome-wide methylation patterns in normal and uniparental early mouse embryos   (Citations: 39)
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In the normal diploid mouse embryo, active demethy- lation of the paternal genome but not of the maternal genome occurs within only a few hours and in a highly coordinated fashion as the zygote proceeds through the first G1 phase. This zygotic demethylation may be necessary to reprogram the sperm genome for somatic development. Immunofluorescence staining with an antibody against 5-methylcytosine
Journal: Human Molecular Genetics - HUM MOL GENET , vol. 10, no. 26, pp. 2983-2987, 2001
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