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Nesiritide Does Not Improve Renal Function in Patients With Chronic Heart Failure and Worsening Serum Creatinine

Nesiritide Does Not Improve Renal Function in Patients With Chronic Heart Failure and Worsening Serum Creatinine,David J. Wang,Thomas C. Dowling,Dean

Nesiritide Does Not Improve Renal Function in Patients With Chronic Heart Failure and Worsening Serum Creatinine   (Citations: 52)
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Published in 2010.
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    • ...Similar results were confirmed in a randomized trial of nesiritide versus nitroglycerin infusion, which led to its FDA approval [51] . Further investigation raised questions as to its efficacy and safety with regard to renal function [52, 53] . However, a larger prospective study of nesiritide in patients with renal dysfunction failed to show harm or benefit with respect to renal function in the treatment of ADHF [54] . In the large ...

    Robb Kociolet al. Organ Cross Talk in the Critically Ill: The Heart and Kidney

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