Sign in
Author
|
Conference
|
Journal
|
Organization
|
Year
|
DOI
Look for results that meet for the following criteria:
since
equal to
before
between
and
Search in all fields of study
Limit my searches in the following fields of study
Agriculture Science
Arts & Humanities
Biology
Chemistry
Computer Science
Economics & Business
Engineering
Environmental Sciences
Geosciences
Material Science
Mathematics
Medicine
Physics
Social Science
Multidisciplinary
Keywords
(6)
Mouse Model
Ryanodine Receptor
Transgenic Mice
catecholaminergic polymorphic ventricular tachycardia
Sudden Death
Ventricular Tachycardia
Related Publications
(2)
Significance analysis of microarrays applied to the ionizing radiation response
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
Subscribe
Academic
Publications
Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia Insights From a RyR2 R4496C Knock-In Mouse Model
Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia Insights From a RyR2 R4496C Knock-In Mouse Model,Nian Liu,Barbara Colombi,Mi
Edit
Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia Insights From a RyR2 R4496C Knock-In Mouse Model
(
Citations: 24
)
BibTex
|
RIS
|
RefWorks
Download
Nian Liu
,
Barbara Colombi
,
Mirella Memmi
,
Spyros Zissimopoulos
,
Nicoletta Rizzi
,
Sara Negri
,
Marcello Imbriani
,
Carlo Napolitano
,
F. Anthony Lai
,
Silvia G. Priori
Published in 2010.
Cumulative
Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
(
circres.ahajournals.org
)
Citation Context
(3)
... Moreover, JTV519 did not prevent delayed afterdepolarizations in myocytes isolated from heterozygous RyR2-R4496C/+ mic
...
Mark D McCauley
,
et al.
Targeting ryanodine receptors for anti-arrhythmic therapy
...Based on the foregoings, we propose that the phenotype of the CASQ2R33Q/R33Q CPVT mouse model is portrayed by an unexpected set of abnormalities including (1) reduced CASQ2 content, possibly attributable to increased degradation of CASQ2-R33Q, (
2
) reduction of SR calcium content, (3) dilatation of junctional SR, and (4) impaired clustering of mutant CASQ2...
...phenotype: (1) reduction of CASQ2 levels (likely attributable to post/translational regulation leading to increased protein degradation, see below) and (
2
) impairment of RyR2 deactivation, as shown by Terentyev et al13 and Qin et al.21 Despite a substantial reduction of CASQ2 seems to be central in recessive CPVT, it is still a matter of debate whether a threshold decrease of CASQ2 is required for eliciting the CPVT phenotype or whether ...
Nicoletta Rizzi
,
et al.
Unexpected Structural and Functional Consequences of the R33Q Homozygo...
...39,
...
Laura Sartiani
,
et al.
Prenatal exposure to carbon monoxide delays postnatal cardiac maturati...
References
(27)
Mutations in the Cardiac Ryanodine Receptor Gene (hRyR2) Underlie Catecholaminergic Polymorphic Ventricular Tachycardia
(
Citations: 173
)
Silvia G. Priori
,
Carlo Napolitano
,
Natascia Tiso
,
Mirella Memmi
,
Gabriele Vignati
,
Raffaella Bloise
,
Vincenzo Sorrentino
,
Gian Antonio Danieli
Published in 2010.
Enhanced Basal Activity of a Cardiac Ca2 Release Channel (Ryanodine Receptor) Mutant Associated With Ventricular Tachycardia and Sudden Death
(
Citations: 34
)
Dawei Jiang
,
Bailong Xiao
,
Lin Zhang
,
S. R. Wayne Chen
Sudden Death in Familial Polymorphic Ventricular Tachycardia Associated With Calcium Release Channel (Ryanodine Receptor) Leak
(
Citations: 36
)
Stephan E. Lehnart
,
Xander H. T. Wehrens
,
Päivi J. Laitinen
,
Steven R. Reiken
,
Shi-Xiang Deng
,
Zhenzhuang Cheng
,
Donald W. Landry
,
Kimmo Kontula
,
Heikki Swan
,
Andrew R. Marks
Protein Kinase A Phosphorylation at Serine2808 of the Cardiac Ca2Release Channel (Ryanodine Receptor) Does Not Dissociate 12.6-kDa FK506Binding Protein (FKBP12.6)
(
Citations: 24
)
Bailong Xiao
,
Cindy Sutherland
,
Michael P. Walsh
,
S. R. Wayne Chen
Published in 2010.
Enhanced Store Overload-Induced Ca2 Release and Channel Sensitivity to Luminal Ca2 Activation Are Common Defects of RyR2 Mutations Linked to Ventricular Tachycardia and Sudden Death
(
Citations: 27
)
Dawei Jiang
,
Ruiwu Wang
,
Bailong Xiao
,
Huihui Kong
,
Donald J. Hunt
,
Philip Choi
,
Lin Zhang
,
S. R. Wayne Chen
Published in 2010.
Sort by:
Citations
(24)
Ryanodine receptors
E Michelle Capes
,
Randall Loaiza
,
Héctor H Valdivia
Journal:
Skeletal Muscle
, vol. 1, no. 1, pp. 1-13, 2011
Targeting ryanodine receptors for anti-arrhythmic therapy
Mark D McCauley
,
Xander H T Wehrens
Journal:
Acta Pharmacologica Sinica - ACTA PHARMACOL SIN
, vol. 32, no. 6, pp. 749-757, 2011
Sarcoplasmic Reticulum Calcium Overloading in Junctin Deficiency Enhances Cardiac Contractility but Increases Ventricular Automaticity
(
Citations: 5
)
Qunying Yuan
,
Guo-Chang Fan
,
Min Dong
,
Beth Altschafl
,
Abhinav Diwan
,
Xiaoping Ren
,
Harvey H. Hahn
,
Wen Zhao
,
Jason R. Waggoner
,
Larry R. Jones
,
W. Keith Jones
,
Donald M. Bers
http://academic.research.microsoft.com/io.ashx?type=5&id=11395746&selfId1=0&selfId2=0&maxNumber=12&query=
Published in 2010.
Unexpected Structural and Functional Consequences of the R33Q Homozygous Mutation in Cardiac Calsequestrin A Complex Arrhythmogenic Cascade in a Knock In Mouse Model
(
Citations: 3
)
Nicoletta Rizzi
,
Nian Liu
,
Carlo Napolitano
,
Alessandra Nori
,
Federica Turcato
,
Barbara Colombi
,
Silvio Bicciato
,
Diego Arcelli
,
Alessandro Spedito
,
Mario Scelsi
,
Laura Villani
,
Giovanni Esposito
http://academic.research.microsoft.com/io.ashx?type=5&id=11782016&selfId1=0&selfId2=0&maxNumber=12&query=
Published in 2010.
Modest Reductions of Cardiac Calsequestrin Increase Sarcoplasmic Reticulum Ca2 Leak Independent of Luminal Ca2 and Trigger Ventricular Arrhythmias in Mice
(
Citations: 3
)
Nagesh Chopra
,
Prince J. Kannankeril
,
Tao Yang
,
Thinn Hlaing
,
Izabela Holinstat
,
Kristen Ettensohn
,
Karl Pfeifer
,
Brandy Akin
,
Larry R. Jones
,
Clara Franzini-Armstrong
,
Björn C. Knollmann
Published in 2010.