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Prognostic Implications ofBaseline Electrocardiogra phic Features andTheir Serial Changes inSubjects With LeftVentricular Hypertrophy

Prognostic Implications ofBaseline Electrocardiogra phic Features andTheir Serial Changes inSubjects With LeftVentricular Hypertrophy,Daniel Levy,Meli

Prognostic Implications ofBaseline Electrocardiogra phic Features andTheir Serial Changes inSubjects With LeftVentricular Hypertrophy   (Citations: 85)
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syndrome. Logistic regression analyses of pooled biennial examinations wereusedtodetermine risk for cardiovascular disease asafunction ofbaseline voltage (sum ofR waveinaVLplusSwaveinV3)andrepolarization andasa function ofserial changes inthese ECGfeatures ofhypertrophy. Theeligible sample consisted of274men(mean age, 60years) and250women(mean age,64years) whocontributed 2660 person-examinations. During follow-up, there were269new cardiovascular events. Compared withsubjects inthefirst quar- tile ofvoltage atbaseline, theage-adjusted oddsratio for cardiovascular disease amongsubjects inthefourth quartile was 3.08 (95%confidence interval (CI), 1.87 to5.07) inmenand3.29 (95%CI,1.78 to6.09) inwomen.Compared withanormal repolarization pattern, thepresence ofsevererepolarization abnormalities wasassociated with anage-adjusted oddsratio of 5.84 (95%CI,3.55 to9.62) inmenand2.47 (95%CI,1.38 to4.42)
Published in 2010.
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