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Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present

Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present,10.1590/S0004-27302007000500012,Arquivos Brasileiros De Endocr

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Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present   (Citations: 2)
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Thyroid cancer in children is usually rare, but in the individuals exposed to radiation risk of disease increases considerably. After the Chernobyl acci- dent in 1986, an over 10-fold maximal elevation in the incidence of thyroid cancer was registered about a decade later, cumulatively resulting in more than a thousand of newly diagnosed cases in children who lived in the ter- ritories of Belarus, Russia, and Ukraine affected by radioactive fallouts. Experience from the epidemic substantially promoted knowledge in clini- cal pediatric oncology, pathology and basic sciences. This article overviews epidemiology, clinical features, results of treatment and follow- up of childhood patients with radiation-induced Chernobyl thyroid cancer in comparison to sporadic cases diagnosed at present. In addition, we dis- cuss general issues of pathology and molecular findings in childhood thy- roid carcinomas. (Arq Bras Endocrinol Metab 2007;51/5:748-762)
Journal: Arquivos Brasileiros De Endocrinologia E Metabologia - ARQ BRAS ENDOCRINOL METABOL , vol. 51, no. 5, 2007
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