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On the relative acidity and basicity of the amino groups of the nucleic acid bases

On the relative acidity and basicity of the amino groups of the nucleic acid bases,10.1007/BF00552495,Theoretical Chemistry Accounts,Richard Lavery,Al

On the relative acidity and basicity of the amino groups of the nucleic acid bases   (Citations: 3)
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Quantum chemical calculations are reported on the deprotonation and protonation of the amino groups of the nucleic acid bases adenine, guanine and cytosine, in an attempt to compare the relative reactivities of these groups. In the light of renewed interest in the amino groups as reactive sites for certain carcinogenic and carcinostatic agents, we discuss the possible significance of our results for the interpretation of these molecular interactions.
Journal: Theoretical Chemistry Accounts - THEOR CHEM ACC , vol. 50, no. 1, pp. 67-73, 1978
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