Academic
Publications
Design, synthesis and biological evaluation of new oxazines with potential antiparasitic activity

Design, synthesis and biological evaluation of new oxazines with potential antiparasitic activity,10.1016/j.tetlet.2007.02.032,Tetrahedron Letters,Dan

Design, synthesis and biological evaluation of new oxazines with potential antiparasitic activity   (Citations: 2)
BibTex | RIS | RefWorks Download
A series of new oxazines with potential antiparasitic activity was prepared using Diels–Alder reactions, based on terpenes derived from eucarvone as dienes and nitrosoarenes with different electronic characteristics as dienophiles. The biological activity was evaluated with in vitro assays against Plasmodium falciparum, Trypanosoma cruzi and Trypanosoma brucei rhodesiense. Some of these oxazines have activities in the 20–50μM range, and may be leaders for the development of novel antiparasitic drugs with improved pharmacological properties.
Journal: Tetrahedron Letters - TETRAHEDRON LETT , vol. 48, no. 14, pp. 2505-2507, 2007
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
Sort by: