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Possibility of Differential Diagnosis of Small Polypoid Lesions in the Gallbladder Using FDG-PET

Possibility of Differential Diagnosis of Small Polypoid Lesions in the Gallbladder Using FDG-PET,10.1016/S1095-0397(00)00100-X,Clinical Positron Imagi

Possibility of Differential Diagnosis of Small Polypoid Lesions in the Gallbladder Using FDG-PET   (Citations: 9)
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Purpose: We discuss three cases of patients with small polypoid lesions of gallbladder in which we successfully differentiated the malignancy or benignity preoperatively using positron emission tomography (PET) scanning with 18F-labelled deoxyglucose (FDG).Methods and Results: The first case involves a 47-year-old woman who had a 15 × 10 mm polypoid lesion of the gallbladder. FDG-PET was performed and revealed no FDG uptake. The histopathological diagnosis was a cholesterol polyp. The second case is a 56-year-old woman who had a 22 × 8 mm polypoid lesion in the neck of the gallbladder and wall-thickening of the fundus. FDG-PET was performed and no FDG uptake was found. The postoperative diagnosis was pseudo-tumorous sludge in the neck and adenomyomatosis of the fundus. The third case is a 77-year-old man who had a 15 × 15 mm polypoid lesion in the gallbladder. PET revealed a focus of FDG uptake at the site of the gallbladder. The histopathologic diagnosis was adenocarcinoma. Focal FDG uptake was the sole indicator of a malignant tumor of the gallbladder.Conclusions: FDG-PET may become one of the most useful tools for the accurate preoperative diagnosis of gallbladder carcinoma.
Journal: Clinical Positron Imaging , vol. 3, no. 5, pp. 213-218, 2000
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