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A gene expression signature as a predictor of survival in breast cencer

A gene expression signature as a predictor of survival in breast cencer,M De Vijver

A gene expression signature as a predictor of survival in breast cencer   (Citations: 397)
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Published in 2002.
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    • ...This view is supported by various independent microarray studies [6, 11, 12, 13, 21, 24, 26, 27]...
    • ...To illustrate its potential we apply this approach to breast cancer datasets from Sorlie et al [25], West et al [27], van ’t Veer et al [26] and de Vijver et al [6]...
    • ...The study of van ’t veer et al preceded a larger study by de Vijver et al [6] which used 295 samples from patients with primary breast carcinomas...
    • ...The curve shows a peak in the range 4 to 6 processes, implying that the 2-process model proposed by the original authors [6] is a sub-optimal interpretation of the data...
    • ...The original split of de Vijver et al [6] are given as dashed curves for comparison...
    • ...Certainly, our analysis suggests that the 2 process split of de Vijver et al [6] is too simple a model and at least 4 main processes are justified by the datasets used...

    L. Carrivicket al. Identification of Prognostic Signatures in Breast Cancer Microarray Da...

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