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Perioperative stress response to carotid endarterectomy: The impact of anesthetic modality

Perioperative stress response to carotid endarterectomy: The impact of anesthetic modality,10.1016/j.jvs.2004.02.002,Journal of Vascular Surgery,Massi

Perioperative stress response to carotid endarterectomy: The impact of anesthetic modality   (Citations: 6)
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ObjectiveSurgery for extracranial carotid artery disease has been challenged by carotid angioplasty stenting because the latter is less invasive and avoids surgical trauma. In fact, the magnitude of the perioperative stress response evoked by carotid endarterectomy (CEA) has never been evaluated. Our aim was to determine the degree of surgical trauma caused by CEA and to define differences related to the use of locoregional or general anesthesia.
Journal: Journal of Vascular Surgery - J VASC SURG , vol. 39, no. 6, pp. 1295-1304, 2004
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    • ...Hypoxia and perioperative cortical hypoperfusion have been established recently as predictors of postoperative delirium and cognitive defi cits [6,9] (Table 1). Moreover, in previous studies, an association between the duration of carotid artery cross-clamping and increased cortisol level was observed, suggesting a positive correlation between cerebral hypoperfusion and excessive cortisol secretion [10]...

    Jakub Kazmierskiet al. Is cortisol the key to the pathogenesis of delirium after coronary art...

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