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Brachial Artery Flow-Mediated Vasodilation in Patients With Cardiac Syndrome X

Brachial Artery Flow-Mediated Vasodilation in Patients With Cardiac Syndrome X,10.1177/0003319707308032,Angiology,Ai-Hsien Li,Bai-Chin Lee,Kuo-Chin Ch

Brachial Artery Flow-Mediated Vasodilation in Patients With Cardiac Syndrome X   (Citations: 2)
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Cardiac syndrome X (CSX) differs from coronary artery disease (CAD) and is characterized by angina, positive stress test, and patent coronary arteries. The probable mechanism is a microvascular disorder associated with endothelial dysfunction. In this study, brachial artery flow-mediated vasodilation was used as well as the endothelin-1 assay to assess endothelial function in patients with cardiac syndrome X (CSX), coronary artery disease (CAD), and healthy controls. All subjects underwent a 2-step brachial artery flow-related vasodilatation test. Serum endothelin-1, one of the most potent constricting factors, was measured for all participants. Patients with CSX had a lower brachial artery dilation ratio than controls but higher than that of CAD patients. Control subjects and CSX patients had higher endothelin-1 levels than CAD patients. CSX patients were found to have worse endothelial function than healthy volunteers, but patients with CAD had even worse endothelium function than CSX patients.
Journal: Angiology , vol. 59, no. 5, pp. 581-586, 2008
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