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Bacterial eradication by clinafloxacin, CI990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies
Bacterial eradication by clinafloxacin, CI990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies,10.1093/jac/41.6
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Bacterial eradication by clinafloxacin, CI990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies
(
Citations: 6
)
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M. Cohen
Journal:
Journal of Antimicrobial Chemotherapy - J ANTIMICROB CHEMOTHER
, vol. 41, no. 6, pp. 605-614, 1998
DOI:
10.1093/jac/41.6.605
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(
www.jac.oupjournals.org
)
Citation Context
(5)
...These suspensions were reincubated at 37 °C for 48 h. The MBC was determined as the lowest concentration of extract which inhibited 100% growth of microorganisms (
Cohen et al., 1998
)...
G. More
,
et al.
Antimicrobial activity of medicinal plants against oral microorganisms
...PD 0305970 was tested at 0.25 ,1 ,2 ,4 , and 8 MIC (0.5 ,2 , and 8 for ciprofloxacin), and samples were plated for bacterial colony counts at 0, 2, 4, 6, and 24 h (
2
)...
...Streptococcus pneumoniae SVI 2.7 0.8 (0.015) 100 (
2
) 69 37 (0.5) S. pyogenes C203d 0.7 0.1 (0.015) 100 (0.5) 17.7 2.1 (0.5)...
Michael D. Huband
,
et al.
In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bact...
...Microbiological studies demonstrated that clinafloxacin is highly active against a broad spectrum of bacterial species (3, 4,
5
, 7, 11)...
...25 0.24 (9) 1.12 (4) 4.6 (20) 206 (13) 55.4 (11) 372 (4) 137 (13) 50 0.38 (26) 1.82 (18) 4.9 (6) 342 (14) 73.7 (8) 468 (17) 175 (23) 100 0.90 (23) 4.36 (25) 5.6 (32) 270 (24) 67.4 (6) 399 (22) 150 (32) 200 1.61 (16) 8.82 (11) 6.0 (17) 262 (12) 68.8 (6) 381 (10) 167 (18) 400 3.52 (22) 21.3 (16) 5.8 (
5
) 235 (8) 74.8 (15) 319 (14) 136 (13)...
EDWARD J. RANDINITIS
,
et al.
Pharmacokinetics of Clinafloxacin after Single and Multiple Doses
...Clinafloxacin is a potent quinolone antibacterial with a broad range of activity that is of potential clinical importance in the management of serious infections, including those caused by many bacteria resistant to a wide variety of other antibiotics (5,
6
, 7, 11, 16, 27)...
EDWARD J. RANDINITIS
,
et al.
Drug Interactions with Clinafloxacin
...Clinafloxacin was shown to be more bactericidal than ciprofloxacin as measured by MBC, in vitro time-kill and in rive time-kill studies [
54
]...
C. E. Nord
.
Use of newer quinolones for the treatment of intraabdominal infections...
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Citations
(6)
Antimicrobial activity of medicinal plants against oral microorganisms
(
Citations: 13
)
G. More
,
T. E. Tshikalangea
,
N. Lall
,
F. Botha
,
J. J. M. Meyer
Journal:
Journal of Ethnopharmacology - J ETHNOPHARMACOL
, vol. 119, no. 3, pp. 473-477, 2008
In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bacterial Gyrase/Topoisomerase Inhibitors with Potent Antibacterial Activities versus Multidrug-Resistant Gram-Positive and Fastidious Organism Groups
(
Citations: 6
)
Michael D. Huband
,
Michael A. Cohen
,
Margaret Zurack
,
Debra L. Hanna
,
Laura A. Skerlos
,
Mark C. Sulavik
,
Glenn W. Gibson
,
Jeffrey W. Gage
,
Edmund Ellsworth
,
Michael A. Stier
,
Stephen J. Gracheck
Journal:
Antimicrobial Agents and Chemotherapy - ANTIMICROB AGENTS CHEMOTHER
, vol. 51, no. 4, pp. 1191-1201, 2007
Pharmacokinetics of Clinafloxacin after Single and Multiple Doses
(
Citations: 4
)
EDWARD J. RANDINITIS
,
JOANNE I. BRODFUEHRER
,
IRENE EISEMAN
,
A. B. Vassos
Journal:
Antimicrobial Agents and Chemotherapy - ANTIMICROB AGENTS CHEMOTHER
, vol. 45, no. 9, pp. 2529-2535, 2001
Drug Interactions with Clinafloxacin
(
Citations: 3
)
EDWARD J. RANDINITIS
,
CHRISTINE W. ALVEY
,
JEFFERY R. KOUP
,
GEORGE RAUSCH
,
ROBERT ABEL
,
NICOLA J. BRON
,
NEIL J. HOUNSLOW
,
ARTEMIOS B. VASSOS
,
ALLEN J. SEDMAN
Journal:
Antimicrobial Agents and Chemotherapy - ANTIMICROB AGENTS CHEMOTHER
, vol. 45, no. 9, pp. 2543-2552, 2001
Clinafloxacin Pharmacokinetics in Subjects with Various Degrees of Renal Function
(
Citations: 2
)
EDWARD J. RANDINITIS
,
JEFFERY R. KOUP
,
GEORGE RAUSCH
,
ROBERT ABEL
,
NICOLA J. BRON
,
NEIL J. HOUNSLOW
,
ARTEMIOS B. VASSOS
,
ALLEN J. SEDMAN
Journal:
Antimicrobial Agents and Chemotherapy - ANTIMICROB AGENTS CHEMOTHER
, vol. 45, no. 9, pp. 2536-2542, 2001