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Management of the contralateral testicle in patients with unilateral testicular cancer

Management of the contralateral testicle in patients with unilateral testicular cancer,10.1007/s00345-009-0410-4,World Journal of Urology,Eugene K. Le

Management of the contralateral testicle in patients with unilateral testicular cancer  
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Patients with a prior history of a germ cell tumor of the testicle are known to have an increased risk of development of a second germ cell tumor in the contralateral testicle. It is believed that all patients who develop a germ cell tumor of the testicle have a precursor lesion know as carcinoma in situ (CIS) or intratubular germ cell neoplasia. Approximately 50% of these patients will subsequently go on to develop a germ cell tumor in the testicle. A biopsy of the contralateral testicle in a patient with a previous history of a germ cell tumor of the testicle has been advocated by some, while others recommend a biopsy only in patients with other risk factors as well. The arguments for biopsy are that intervention may be used to prevent the development of a second germ cell tumor when CIS is detected. In this review we present the arguments for and against a biopsy of the contralateral testicle, review the techniques of biopsy as well as its complications, and discuss the interventions employed to prevent CIS from progressing.
Journal: World Journal of Urology - WORLD J UROL , vol. 27, no. 4, pp. 421-426, 2009
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