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Early-Stage Hodgkin's Lymphoma

Early-Stage Hodgkin's Lymphoma,10.1056/NEJMra1003733,New England Journal of Medicine,James O. Armitage

Early-Stage Hodgkin's Lymphoma   (Citations: 4)
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Journal: New England Journal of Medicine - N ENGL J MED , vol. 363, no. 7, pp. 653-662, 2010
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    • ... These results raise several questions: first, what is a good balance between chemotherapy and radiotherapy in patients with localized Hodgkin lymphoma? Second, is it possible to reduce the intensity of therapy in some patients? Third, when can results from a randomized study be considered definitive in patients with Hodgkin lymphoma? Finally, what is the best end point for future studies in patients with Hodgkin lymphoma?

      The current treatment for localized Hodgkin lymphoma—a short course of chemotherapy plus low-dose involved-field radiotherapy—cures over 90% of patients...

    Olivier Casasnovaset al. Hematological cancerLocalized non-bulky Hodgkin lymphoma—future questi...

    • ... Chemotherapy and radiation therapy have been shown to be very effective at causing HL remission, but morbidity and mortality associated with these treatments is substantial ...

    Susan M. Varnumet al. Plasma Biomarkers for Detecting Hodgkin's Lymphoma in HIV Patients

    • ...Long follow-up of patients who were cured of Hodgkin lymphoma with radiotherapy, chemotherapy, or a combination of the two modalities has shown that the frequency of late complications (predominantly cardiovascular disease and second malignancies) is a major issue [4]...
    • ...Similar trials to those in the United States are being conducted in Europe [4]...

    James O. Armitageet al. The Importance of Testing PET-Directed Therapy in Patients with Hodgki...

    • ...While the results from many centers in the West have been published identifying prognostic factors and as a result need for minimizing chemotherapy and radiotherapy in early stage good risk patients [2, 3], limited information is available from countries with limited resources [5–10]...

    Prasanth Ganesanet al. Hodgkin’s lymphoma—long-term outcome: an experience from a tertiary ca...

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