A new scoring system to differentiate benign from malignant adnexal masses

A new scoring system to differentiate benign from malignant adnexal masses,10.1067/mob.2003.176,American Journal of Obstetrics and Gynecology,Juan Lui

A new scoring system to differentiate benign from malignant adnexal masses   (Citations: 13)
BibTex | RIS | RefWorks Download
Objective: The purpose of this study was to develop and cross-validate a new sonographic scoring system for differentiation between benign and malignant adnexal masses. Study Design: This study was conducted in a tertiary care university hospital. In the first part of the study, we used a multivariate logistic regression analysis to develop a scoring system that was based on morphologic and Doppler sonographic data for 705 adnexal masses in 665 patients who were diagnosed and treated at our institution from January 1995 to June 2001. The scoring system was designed to use only those parameters that are found to be independent predictors of malignancy. In the second part of the study, we prospectively cross-validated this scoring system in a series of 90 adnexal masses in 86 patients between July 2001 and March 2002. With the use of the area under the curve of the respective ROC curves, we compared the new scoring system with other scoring systems. Results: Multivariate logistic regression analysis revealed that the only independent predictor parameters were thick papillary projections, solid areas, central flow, and velocimetric features of high velocity and low resistance. In the prospective cross-validation study, our scoring system had the best diagnostic performance (area under the curve, 0.98) compared with Sassone (area under the curve, 0.89; P= .017), De Priest (area under the curve, 0.92; P= .048), and Ferrazzi (area under the curve, 0.90; P= .013) scoring systems. Conclusion: Our new sonographic scoring system had a better diagnostic performance than three previously published scoring systems. (Am J Obstet Gynecol 2003;188:685-92.)
Journal: American Journal of Obstetrics and Gynecology - AMER J OBSTET GYNECOL , vol. 188, no. 3, pp. 685-692, 2003
Cumulative Annual
View Publication
The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
    • ...The addition of color-flow Doppler to measure the resistance in the blood vessels supplying the ovary may provide additional information to distinguish between benign and malignant masses, thus enhancing the specificity of TVS; however, this finding has not been consistent [13,14]...

    Christine S. Walshet al. Contemporary progress in ovarian cancer screening

Sort by: