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Cranial ultrasound findings in well newborn Ugandan infants

Cranial ultrasound findings in well newborn Ugandan infants,10.1136/adc.2009.174607,Archives of Disease in Childhood-fetal and Neonatal Edition,CF Hag

Cranial ultrasound findings in well newborn Ugandan infants   (Citations: 1)
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BackgroundThere has been no study assessing cranial ultrasound (cUS) scans in newborn infants born in equatorial Africa.ObjectiveTo assess the cUS scans of apparently well newborn term Ugandan infants and to correlate the findings with perinatal data.MethodsAn observational study of apparently healthy postnatal ward term Ugandan infants at Mulago Hospital, Makerere University Hospital, Kampala, Uganda.ResultsData from 112 infants scanned at a median age of 1.4 postnatal days were analysed. Only 57 (51%) infants had scans considered normal, including 30 infants with isolated focal peritrigonal white matter (WM) echogenicity that was very common, occurring in 60 (53%) of infants. More extensive WM echogencities were seen in nine (7.5%) and focal unilateral central grey matter echogenicity in eight (6.5%) infants. Haemorrhage was not common. Subependymal pseudocysts (SEP) and choroid plexus cysts (CPC) occurred in 19.6% of infants each. Four infants only had lenticulostriate vasculopathy. No correlation was found between mode of delivery, birth weight, head circumference or gestational age, maternal HIV status and any cUS abnormality.ConclusionsApparently well term-born Ugandan infants frequently have abnormalities on cUS. These are mainly increased WM echogenicity, SEP and CPC. These may relate to the reported high incidence of congenital infections in this population but this remains to be confirmed. The observations provide baseline data for comparison with scans from sick infants from similar communities and are also important for studies in which cUS will be used to assess progress.
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    • ...To determine the incidence of abnormalities seen on cranial ultrasound in a population of low-risk African babies, ~100 newborn infants on the postnatal ward underwent a scan using the standard 11 views as soon as possible after birth [32]...
    • ...This is the first study of therapeutic hypothermia in a low resource setting that will include detailed cranial ultrasound imaging, have a comparative control or typical population [32] and a neonatal neurological assessment in the 3 rd week after birth and at 18-22 months...

    Nicola J Robertsonet al. Pilot randomized trial of therapeutic hypothermia with serial cranial ...

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