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Goodpasture syndrome during the course of a Schönlein-Henoch purpura

Goodpasture syndrome during the course of a Schönlein-Henoch purpura,10.1053/ajkd.2002.32799,American Journal of Kidney Diseases,Luis Carreras,Rafael

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Goodpasture syndrome during the course of a Schönlein-Henoch purpura   (Citations: 431)
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Two months after surgical resection of a bronchogenic carcinoma, a 69-year-old patient presented with Schönlein-Henoch purpura with kidney involvement followed by pulmonary hemorrhage. The presence of an IgA linear pattern on the kidney biopsy specimen and circulating anti-glomerular basement membrane (GBM) IgA antibodies led to the diagnosis of Goodpasture syndrome, which implies the possibility that the well-known pulmonary involvement during the course of Schönlein-Henoch purpura could be caused by Goodpasture syndrome in certain cases. In cases of glomerulonephropathy with lung involvement, clinicians should not limit their investigations to anti-GBM IgG.
Journal: American Journal of Kidney Diseases - AMER J KIDNEY DIS , vol. 39, no. 5, pp. 1-4, 2002
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    • ...Recently, Carreras et al. [33] reported a 69-year-old patient with Henoch-Schönlein purpura with kidney involvement followed by pulmonary hemorrhage...

    Luis J. Jara, et al. Pulmonary-Renal vasculitic disorders: Differential diagnosis and manag...

    • ...Si el cuadro renal se acompaña de hemorragia pulmonar generalmente se le da el nombre de síndrome de Goodpasture; a la fecha actual se han reportado cinco casos confirmados de esta entidad generada por depósitos lineales de inmunoglobulina A (siendo este el primero en ser reportado en la literatura en español), los cuales se han confirmado todos en la biopsia renal (5-9), método recomendado como el ideal para ...
    • ...Carreras y col (9) también recientemente describen un paciente con una secuencia semejante a la actual, lo cual demuestra la posibilidad de encontrar activa participación del sistema inmunológico de la inmunoglobulina A en varios eventos clínico y patológicos (10, 11)...

    CÉSAR A. RESTREPOMANIZALES. Síndrome de Goodpasture por IgA en un paciente con diagnóstico clínico...

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