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Risk assessment as a guide for the prevention of the many faces of venous thromboembolism

Risk assessment as a guide for the prevention of the many faces of venous thromboembolism,10.1016/j.amjsurg.2009.10.006,American Journal of Surgery,Jo

Risk assessment as a guide for the prevention of the many faces of venous thromboembolism   (Citations: 5)
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BackgroundApproximately 900,000 cases of deep vein thrombosis and pulmonary embolism occur annually in the United States, and one-third lead to the patient's death. A variety of surgical factors contribute to Virchow's triad of venous stasis, vascular injury, and hypercoagulability, including intraoperative venous distension and microvascular endothelial damage. Patients also may have individual risk factors such as a history of thromboembolism, cancer, advanced age, or a genetic trait linked to hypercoagulation. This article discusses recent trends in the development and validation of venous thromboembolism risk scores, including the results of a large validation study.
Journal: American Journal of Surgery - AMER J SURG , vol. 199, no. 1, pp. S3-S10, 2010
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    • ...The effect of anesthesia on vasodilation in surgical patients is recognized for general [34] and regional techniques, with additional venous distension resulting from the use of muscle relaxants [35]...
    • ...These disorders include genetic deficiencies of protein C or protein S, antithrombin mutations of factor V Leiden, and prothrombin deficiencies [35, 39]...

    D. Marslandet al. Venous thromboembolic prophylaxis for hip fractures

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