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Ki67 expression in different epithelial types in columnar lined oesophagus indicates varying levels of expanded and aberrant proliferative patterns

Ki67 expression in different epithelial types in columnar lined oesophagus indicates varying levels of expanded and aberrant proliferative patterns,10

Ki67 expression in different epithelial types in columnar lined oesophagus indicates varying levels of expanded and aberrant proliferative patterns   (Citations: 6)
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Journal: Histopathology , vol. 47, no. 2, pp. 132-140, 2005
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    • ...Olvera et al. [62] recently demonstrated abnormal patterns of Ki67 immunoreactivity, a marker of cell proliferation, in various types of CLE...
    • ...In contrast to oxyntic mucosa, expanded Ki67 expression from the lower (= normal) towards the middle third of the foveolar pit was detected in different types of CLE, following a step wise increase from oxyntic, onxytocardiac and cardiac mucosa to intestinal metaplasia, low-, high-grade dysplasia and adenocarcinoma [62]...
    • ...Frequency of aberrant Ki67 expression within surface and foveolar epithelium in cardiac mucosa showed a stepwise increase from cardiac mucosa and intestinal metaplasia towards low-, highgrade dysplasia and adenocarcinoma [62]...
    • ...Aberrant Ki67 expression was absent in oxyntic and oxyntocardiac mucosa [62]...
    • ...Taken together, these data suggest that when compared to oxyntocardiac mucosa, cardiac mucosa may signify a switch towards “malignant” progression [38, 62]...

    Johannes Lenglingeret al. Diagnosis of Gastroesophageal Reflux Disease (GERD)

    • ...However, CM usually shows histologic evidence of damage by the gastric refluxate [32], including evidence of increased cellular proliferation as measured by increased Ki-67 activity [51]...

    Xiangdong Buet al. Body Mass Index is Associated with Barrett Esophagus and Cardiac Mucos...

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