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Incidental focal solid liver lesions: diagnostic performance of contrast-enhanced ultrasound and MR imaging

Incidental focal solid liver lesions: diagnostic performance of contrast-enhanced ultrasound and MR imaging,10.1007/s00330-009-1700-3,European Radiolo

Incidental focal solid liver lesions: diagnostic performance of contrast-enhanced ultrasound and MR imaging   (Citations: 1)
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Objective  To prospectively assess the diagnostic performance of contrast-enhanced ultrasound (CEUS) and MR imaging in incidental solid focal liver lesions not characterised on ultrasound. Materials and methods  Forty-seven patients with 50 lesions underwent MR imaging and CEUS: 24 focal nodular hyperplasias (FNH), 11 adenomas, 10 haemangiomas, 1 focal fatty change and 4 malignant lesions were identified. Two experienced radiologists randomly reviewed contrast-enhanced MR imaging and CEUS data, and provided the most likely diagnosis. Sensitivity (Se), specificity (Sp), likelihood ratios (LR) and kappa value were calculated. Results  A histotype diagnosis was obtained in 66–52% with MR imaging and 52–53% with CEUS, respectively, for both readers. Se, Sp and LR for haemangioma were 100–100, 100–100 and 78–78 with MR imaging and 89–89, 100–100 and 68–70 with CEUS; for FNH with MR imaging they were 88–63, 96–100 and 23–34 and 74–67, 88–96 and 6–17 with CEUS. If the diagnosis of haemangioma was uncertain with CEUS, MR imaging always confirmed the diagnosis. If the diagnosis of FNH was uncertain with either CEUS or MR imaging, the other imaging technique confirmed the diagnosis in approximately half the cases. Conclusion  Both CEUS and MR imaging have a high diagnostic performance in incidental focal liver lesions and are complementary when diagnosis is uncertain.
Journal: European Radiology - EUROPEAN RADIOL , vol. 20, no. 7, pp. 1715-1725, 2010
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    • ...Soussan et al. [16] presented an interesting study evaluating the role of CEUS in the characterization of solid focal liver lesions in comparison to contrast-enhanced MR imaging...
    • ...This study [16] also raised the challenging topic of incidental focal liver lesion characterization by CEUS and the potential added diagnostic value provided by CEUS to the other imaging techniques...
    • ...By excluding patients with a history of cancer and chronic liver disease, Soussan et al. [16] reduced the pretest probability of malignancy in focal liver lesions due to the high prevalence of malignant lesions detected in these patient categories...

    Emilio Quaia. The real capabilities of contrast-enhanced ultrasound in the character...

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