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Assessment of Mitral Annulus Velocity by Doppler Tissue Imaging in the Evaluation of Left Ventricular Diastolic Function

Assessment of Mitral Annulus Velocity by Doppler Tissue Imaging in the Evaluation of Left Ventricular Diastolic Function,10.1016/S0735-1097(97)88335-0

Assessment of Mitral Annulus Velocity by Doppler Tissue Imaging in the Evaluation of Left Ventricular Diastolic Function   (Citations: 662)
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Objectives. This study assessed the clinical utility of mitral annulus velocity in the evaluation of left ventricular diastolic function.Background. Mitral inflow velocity recorded by Doppler echocardiography has been widely used to evaluate left ventricular diastolic function but is affected by other factors. The mitral annulus velocity profile during diastole may provide additional information about left ventricular diastolic function.Methods. Mitral annulus velocity during diastole was measured by Doppler tissue imaging (DTI) 1) in 59 normal volunteers (group 1); 2) in 20 patients with a relaxation abnormality as assessed by Doppler mitral inflow variables (group 2) at baseline and after saline loading; 3) in 11 patients (group 3) with normal diastolic function before and after intravenous nitroglycerin infusion; and 4) in 38 consecutive patients (group 4) undergoing cardiac catheterization in whom mitral inflow velocity and tau as well as mitral annulus velocity were measured simultaneously.Results. In group 1, mean ± SD peak early and late diastolic mitral annulus velocity was 10.0 ± 1.3 and 9.5 ± 1.5 cm/s, respectively. In group 2, mitral inflow velocity profile changed toward the pseudonormalization pattern with saline loading (deceleration time 311 ± 84 ms before to 216 ± 40 ms after intervention, p Conclusions. Mitral annulus velocity determined by DTI is a relatively preload-independent variable in evaluating diastolic function.
Journal: Journal of The American College of Cardiology - J AMER COLL CARDIOL , vol. 30, no. 2, pp. 474-480, 1997
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