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Antenatal Vitamin A Supplementation Increases Birth Weight and Decreases Anemia among Infants Born to Human Immunodeficiency Virus–Infected Women in Malawi

Antenatal Vitamin A Supplementation Increases Birth Weight and Decreases Anemia among Infants Born to Human Immunodeficiency Virus–Infected Women in M

Antenatal Vitamin A Supplementation Increases Birth Weight and Decreases Anemia among Infants Born to Human Immunodeficiency Virus–Infected Women in Malawi   (Citations: 47)
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Journal: Clinical Infectious Diseases - CLIN INFECT DIS , vol. 35, no. 5, pp. 618-624, 2002
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    • ... found no evidence of benefit of vitamin A on the risk of MTCT of HIV (RR = 1.06, 95% CI = 0.89–1.26; n = 7,528) based on the findings of 3 trials that provided oral vitamin A daily [,,...

    Usha Ramakrishnan. A Review of the Benefits of Nutrient Supplements during Pregnancy: Fro...

    • ... n’ont démontré aucun bénéfice de la vitamine A sur la TME du VIH (RR = 1,06; IC 95% = 0,89–1,26; n = 7528) dans une méta-analyse récente incluant 4 études, dont 3 (Afrique du Sud, Tanzanie, Malawi) apportant la vitamine A en complémentation orale quotidiennement [,,...

    Usha Ramakrishnan. Revue des bénéfices des compléments alimentaires durant la grossesse: ...

    • ... no hallaron pruebas a favor del beneficio de la vitamina A sobre el riesgo de TMI del VIH (RR = 1,06; IC del 95% = 0,89 a 1,26; n = 7.528), basándose en los datos de 3 ensayos en los que se suministró vitamina A por vía oral diariamente [,,...

    Usha Ramakrishnan. Una revisión de los beneficios del aporte complementario de nutrientes...

    • ...In a trial in Malawi, 697 HIV-infected pregnant women were randomized to daily administration of iron and folate throughout pregnancy until delivery, either alone or in combination with vitamin A (3 mg retinol). All women also received 30 mg of retinol at 6 weeks postpartum as part of standard of care. There were no differences between the two groups on overall rates of MTCT of HIV at 6 weeks (vitamin A 26.6%, placebo 27.8%; p = 0.76) or 24 months postpartum (vitamin A 27.7%, placebo 32.8%; p = 0.21). However, maternal vitamin A supplementation was associated with a reduced rate of MTCT of HIV among a subgroup of infants who were HIV-negative by polymerase chain reaction (PCR) at 6 weeks. This observed effect was presumably attributable to a reduction in HIV transmission via breastfeeding (2.8 vs. 7.7% at 24 months; p = 0.04). However, breastfeeding status was not specifically examined in this trial, which constrains interpretation of findings [...

    Saurabh Mehtaet al. Nutritional Interventions in HIV-Infected Breastfeeding Women

    • ...En un ensayo realizado en Malawi se asignó aleatoriamente a 697 mujeres gestantes infectadas por el VIH a la administración diaria de hierro y folato durante todo el embarazo hasta el momento del parto, bien sea solos o en combinación con vitamina A (3 mg de retinol). Todas las mujeres recibieron también 30 mg de retinol al cabo de 6 semanas después del parto como parte del protocolo asistencial. No se registraron diferencias entre ambos grupos en las tasas globales de TMAH del VIH al cabo de 6 semanas del parto (vitamina A: 26.6%; placebo: 27.8%; p = 0.76) ni al cabo de 24 meses del parto (vitamina A: 27.7%; placebo: 32.8%; p = 0.21). No obstante, el aporte complementario de vitamina A a la madre se asociaba a una reducción de la tasa de TMAH del VIH en un subgrupo de lactantes que fueron VIH negativos por la reacción de cadenas de polimerasas (RCP) al cabo de 6 semanas. Este efecto observado era presumiblemente atribuible a una reducción de la transmisión del VIH a través del amamantamiento (2.8 frente a 7.7% al cabo de 24 meses; p = 0.04). No obstante, en este ensayo no se examinó específicamente el estado de lactancia materna, lo cual restringe la interpretación de los resultados [...

    Saurabh Mehtaet al. Intervenciones nutricionales en mujeres lactantes infectadas por el VI...

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