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Prostate Cancer Prevention Trial and European Randomized Study of Screening for Prostate Cancer Risk Calculators: A Performance Comparison in a Contemporary Screened Cohort

Prostate Cancer Prevention Trial and European Randomized Study of Screening for Prostate Cancer Risk Calculators: A Performance Comparison in a Contem

Prostate Cancer Prevention Trial and European Randomized Study of Screening for Prostate Cancer Risk Calculators: A Performance Comparison in a Contemporary Screened Cohort   (Citations: 4)
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BackgroundSeveral models can predict the risk of prostate cancer (PCa) on biopsy.
Journal: European Urology - EUR UROL , vol. 58, no. 4, pp. 551-558, 2010
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    • ... The NRI measures the reclassification of men from one risk category to another by addition of the genetic information to the PSA and age prediction model, and the extent of clinical utility can be evaluated by the magnitude of the NRI. The IDI does not consider risk thresholds; rather it is the mean of increments and decrements in estimated probabilities of prostate cancer for cases and non cases, comparing models. Since the NRI measurement is heavily dependent on the threshold levels used, we used a threshold probability between 15% and 45%, similar to those previously reported in such clinical context ...

    Ricardo J. T. Ribeiroet al. Performance of an Adipokine Pathway-Based Multilocus Genetic Risk Scor...

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