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T Lymphocyte

Overexpression of Interleukin10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor-Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes

Overexpression of Interleukin10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor-Deficient Mice by Altering Lymphocyte and Macropha

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Overexpression of Interleukin10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor-Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes (Citations: 131)


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Journal: Circulation Research - CIRC RES , vol. 90, no. 10, pp. 1064-1071, 2002

DOI: 10.1161/01.RES.0000018941.10726.FA

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Citation Context (19)

- ...
  
  By contrast, T_H2-associated cytokines, particularly IL-10, seem to have a protective role, as they block the formation of pathogenic M1-like macrophages in atherosclerotic plaque...
Peter J. Murray, et al. Protective and pathogenic functions of macrophage subsets
- ...Numerous studies have demonstrated that a systemic or local change in the level of interleukin�10 not only attenuates atheroscle� rosis development [19, 28, 29] but also decreases the damage of tissues [30]...
K. A. Blagodatskikh, et al. The polymorphisms G(−174)C in IL6 gene and G(−1082)A in IL10 gene are ...
- ...been proven to retard atherosclerosis in apoE �/� and LDLR �/� mice [6, 8, 12, 13]...
Min Guo, et al. Inhibition of IFN Regulatory Factor1 Down-Regulate Th1 Cell Function i...
- ... This T_H1 cytokine cascade is counterbalanced by the presence of antiatherogenic T_H2 cytokines, including interleukin (IL)-10...
Valentina Kon, et al. Atherosclerosis in chronic kidney disease: the role of macrophages
- ... When fat-fed low-density lipoprotein receptor (Ldlr)−/− mice, which develop hypercholesterolaemia and atherosclerotic plaques, were transplanted with IL-10-transgenic bone marrow cells, there was a 47% decrease in the atherosclerotic lesion size and an 80% decrease in the necrotic core area compared with mice that received wild-type bone marrow cell...
Ira Tabas. Macrophage death and defective inflammation resolution in atherosclero...

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Citations (131)

Protective and pathogenic functions of macrophage subsets (Citations: 2)

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Journal: Journal of Asian Earth Sciences - J ASIAN EARTH SCI , vol. 42, no. 5, pp. 1066-1073, 2011


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Keywords (1)

Overexpression of Interleukin10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor-Deficient Mice by Altering Lymphocyte and Macropha

Citation Context (19)

Peter J. Murray, et al. Protective and pathogenic functions of macrophage subsets

K. A. Blagodatskikh, et al. The polymorphisms G(−174)C in IL6 gene and G(−1082)A in IL10 gene are ...

Min Guo, et al. Inhibition of IFN Regulatory Factor1 Down-Regulate Th1 Cell Function i...