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Inhibition of the SDF-1/CXCR4 Axis Attenuates Neonatal Hypoxia-Induced Pulmonary Hypertension

Inhibition of the SDF-1/CXCR4 Axis Attenuates Neonatal Hypoxia-Induced Pulmonary Hypertension,10.1161/CIRCRESAHA.109.197533,Circulation Research,K. C.

Inhibition of the SDF-1/CXCR4 Axis Attenuates Neonatal Hypoxia-Induced Pulmonary Hypertension   (Citations: 6)
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Journal: Circulation Research - CIRC RES , vol. 104, no. 11, pp. 1293-1301, 2009
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    • ...Young et al. [26] recently used a neonatal mouse model of pulmonary hypertension and found that the inhibition of CXCR4 activity significantly decreased hypoxia-induced pulmonary hypertension...
    • ...Young et al. [26] and Gambaryan et al. [27] recently reported that inhibition of CXCR4 activity significantly decreased hypoxia-induced pulmonary hypertension in mice, but Young et al. only used neonatal mice [26]...
    • ...Young et al. [26] and Gambaryan et al. [27] recently reported that inhibition of CXCR4 activity significantly decreased hypoxia-induced pulmonary hypertension in mice, but Young et al. only used neonatal mice [26]...

    Lunyin Yuet al. Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypert...

    • ...Other models of SDF-1/CXCR4 inhibition involve the use of antibodies and indicate roles for this signaling complex in neonatal hypoxia-induced pulmonary hypertension (Young et al. 2009) and in non-small cell lung cancer (for a review, see Otsuka and Bebb 2008)...

    Wen-Cheng Chenet al. Lung defects in neonatal and adult stromal-derived factor–1 conditiona...

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