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Intramyocardial Fibroblast Myocyte Communication

Intramyocardial Fibroblast Myocyte Communication,10.1161/CIRCRESAHA.109.207456,Circulation Research,R. Kakkar,R. T. Lee

Intramyocardial Fibroblast Myocyte Communication   (Citations: 11)
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Journal: Circulation Research - CIRC RES , vol. 106, no. 1, pp. 47-57, 2010
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    • ...However, there is increasing evidence that in addition to acting as a source of extracellular matrix, cardiac fibroblasts may play a significant physiological role in the myocardium, including paracrine signalling to cardiac myocytes [4, 5]. Indeed, the recent demonstration that cardiac fibroblast depletion in vivo leads to loss of protective and adaptive hypertrophic responses to pressure overload underscores the importance of this cell ...
    • ...There is increasing evidence for the role of fibroblasts in paracrine signalling in the heart [5] including via fibroblast derived endothelin-1 [30], LIF [31], cardiotrophin-1 [32], IL-6 [33] and periostin [34]...

    Pankaj K. Bhavsaret al. Clenbuterol Induces Cardiac Myocyte Hypertrophy via Paracrine Signalli...

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